12.07.2015 Views

Analysis of genome-scale count data in Bioconductor

Analysis of genome-scale count data in Bioconductor

Analysis of genome-scale count data in Bioconductor

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Example: Cancer <strong>data</strong>set• RNA-seq <strong>data</strong> from Tuch et al (2010)• Compar<strong>in</strong>g oral squamous cell carc<strong>in</strong>oma tissue tomatched healthy oral tissue• 6 samples, paired designSample DescriptionN8 healthy oral tissue from patient 8T8 oral tumour tissue from patient 8N33 healthy oral tissue from patient 33T33 oral tumour tissue from patient 33N51 healthy oral tissue from patient 51T51 oral tumour tissue from patient 51*Ignore paired design for now and treat as simple comparison <strong>of</strong> healthy and tumour groups

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