12.07.2015 Views

Analysis of genome-scale count data in Bioconductor

Analysis of genome-scale count data in Bioconductor

Analysis of genome-scale count data in Bioconductor

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Mean-dispersion relationship• There is evidence <strong>of</strong> that the value <strong>of</strong> thedispersion parameter varies with theexpression level <strong>of</strong> the tag• Noted by Anders and Huber (2010)• Generally, dispersion is larger for lowabundance tags and decreases asabundance <strong>in</strong>creases

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