Conference Program - ABRF 2011 - Association of Biomolecular ...

Vendor Presentations — ContinuedTuesday, February 22 — 12:00 pm – 1:30 pmAlyssum Room, Level 3Exhibit Booth: 214The Latest Solutions for Metabolomicsand Small Molecule ResearchSpeaker: Aiko Barsch, Bruker Daltonik GmbHMetabolomics nowadays has several analytical challenges toovercome. The identification of metabolites is often defined asthe major bottleneck in metabolomics applications as well as ingeneral small molecule research.The confident generation of molecular formulae is the first stepin the identification of unknowns. Especially for m/z values above500, the number of ambiguous assignments increases exponentially.maXis TM Ultra high resolution Q-TOF accurate mass andisotopic pattern data from MS and MS/MS spectra significantlyextends the m/z range for reliable formula suggestions. The molecularformula can then be queried against public databasesto quickly match already known compounds. Hyphenating gaschromatography with soft atmospheric pressure ionisation(APCI) to high resolution Q-TOF-MS technology can preservethe molecular ion information which enables the identificationof unknowns in GC-MS data.One crucial advantage of applying maXis UHR-TOF in untargetedmetabolomic studies is the speed of analysis by couplingU-HPLC systems without compromising the performance interms of mass accuracy or resolution even at high acquisitionrates up to 20Hz. Overall, the sample throughput is increased,thus addressing the necessity of handling large sample numbersneeded for statistically relevant data.Grand Oaks Ballroom,Rooms N&O, Level 2Exhibit Booth: 501Breakthrough Solutions for Proteomics,Biomarker, and Lipidomics ResearchSpeakers: Doug Simmons and Jenny Albanese, AB SCIEXJoin us for lunch and learn about powerful new breakthrough innovationsthat can really boost your productivity in proteomics,biomarker, and lipidomics research!Begonia Room, Level 3Exhibit Booth: 108Recent Developments in WatersMetabolomics and Lipidomics BiomarkerTechnologiesSpeaker: Henry Shion, Principal Applications Scientist,WatersWe will be discussing innovations in metabolomic/lipidomicseparations with UPLC, comprehensive data collection with MSEand QuanTOF technology, and advanced data processing anddatabase searching.Vendor Presentations124 • ABRF 2011 — Technologies to Enable Personalized Medicine