Monday, February 21 (Continued)12:00 pm – 1:30 pm Vendor and Demo Stage PresentationsSee pages 120 and 126 for detailed information.1:30 pm – 3:00 pm Concurrent Research Group Presentations(R4) Joint Session: Protein Sequencing Research Group (PSRG) & Glycoprotein Research Group (gPRG)Level 2, Grand Oaks Ballroom R/S(R4a) PSRG <strong>2011</strong> Study: Sensitivity Assessment for Terminal Sequencing Techniques Using an UnknownProteinSession Organizer: Jim Walters, Sigma AldrichPresenters: Kwasi Mawuenyega, Washington University School <strong>of</strong> Medicine, Wendy Sandoval, Genentech, Inc., SteveSmith, University <strong>of</strong> Texas, and Jim Walters, Sigma Aldrich(R4b) gPRG: Toward Consensus on Glycan Analysis: Reliable Methods and ReproducibilitySession Organizer & Presenter: Joseph Zaia, Boston University(R5) Joint Session: Nucleic Acids Research Group (NARG) & Microarray Research Group (MARG)Level 2, Grand Oaks Ballroom P/QDaily <strong>Program</strong>(R5a) Determining miRNA Expression Levels in Degraded RNA Samples Using Real-Time RT-qPCR andMicroarray TechnologiesSession Organizer: Sridar Chittur, State University <strong>of</strong> New York at AlbanyPresenters: Sridar Chittur, State University <strong>of</strong> New York at Albany, and Scott Tighe, University <strong>of</strong> Vermont(R5b) Microarray Research Group Projects, 2010-11Session Organizer: Don A. Baldwin, Molecular Pr<strong>of</strong>iling Facility, University <strong>of</strong> PennsylvaniaPresenters: Nadereh Jafari, Northwestern University, and Natalia Reyero-Vinas, Jackson State University(W7) Cellular 3D Imaging*Level 2, Grand Oaks Ballroom N/OSession Organizer: Richard Cole, Wadsworth Center, New York State Department <strong>of</strong> Health(W7-1) 3D Cellular Imaging: Beyond the Simple Imaging ParadigmRichard Cole, Wadsworth Center, New York State Department <strong>of</strong> Health(W7-2) Basics <strong>of</strong> Colocalization AnalysesJudith Lacoste, Cell Imaging and Analysis Network, Department <strong>of</strong> Biology, McGill University*A Leica confocal microscope, provided by Leica Microsystems, will be featured in this session in Grand Oaks B.Leica Scanner — Dedicated to advancing biomolecular core facilitiesThe <strong>ABRF</strong> will host a Leica SP5 II confocal equipped with a tandem scanner. This Confocal covers a broad range <strong>of</strong>requirements in confocal imaging — with the full array <strong>of</strong> scan speeds at highest resolution. With its high-efficiency SPdetection (five channels simultaneously) and the optional AOBS (Acousto-Optical Beam Splitter), the system deliversbright, noise-free images with minimal photo damage at high speed. Additionally, there will be available the latestAutoquant’s advanced image deconvolution and 3D visualization s<strong>of</strong>tware for life science researchers.Imaging sessions include:• Co-registration & deconvolution “hands-on”• Confocal microscope & deconvolution s<strong>of</strong>tware on-site• Opportunity to image and analyze “your” sample (physical or digital file from your scope)• Performance testing: point spread functions, spectral calibration & beyond• Core management session/round tables• Networking for imaging core personnel3:15 pm – 4:15 pm <strong>ABRF</strong> Award Lecture: Sir Alec John Jeffreys — Level 1, Exhibit Ballroom C(Sponsored by Agilent Technologies.)22 • <strong>ABRF</strong> <strong>2011</strong> — Technologies to Enable Personalized Medicine
4:15 pm – 4:45 pm Afternoon Refreshment Break — Level 2, Grand Oaks Ballroom, Exhibit Hall4:45 pm – 6:00 pm Concurrent Workshop Sessions(W8) Successful Production <strong>of</strong> Functional ProteinsLevel 2, Grand Oaks Ballroom R/SSession Organizer: Jeff Culp, Pfizer, Inc.(W8-1) Successful Protein ProductionJeff Culp, Pfizer, Inc.(W8-2) Overcoming Problems in Protein Expression and PurificationBill Gillette, SAIC-Frederick, Inc., National Cancer Institute at Frederick(W8-3) When Proteins Misbehave, Try Adding a Little PressureRobert M. Petrovich, National Institute <strong>of</strong> Environmental Health Sciences Laboratory <strong>of</strong> Structural Biology(W9) Therapeutic Antibodies: Over-Hyped “Magic Bullet”, or Under-Explored Technology?Level 2, Grand Oaks Ballroom P/QSession Organizer: Dan L. Crimmins, Washington University School <strong>of</strong> MedicinePresenters: Dan L. Crimmins, Washington University School <strong>of</strong> Medicine, John Harlan, Abbott Laboratories, and FrancesWeis-Garcia, Memorial Sloan-Kettering Cancer Center(W10) Identification <strong>of</strong> Mechanism-Based Biomarkers and Drug Targets Using Pathway AnalysisLevel 2, Grand Oaks Ballroom N/OSession Organizer: Alexander Kel, geneXplain GmbH(W10-1) GeneXplain — Identification <strong>of</strong> Causal Biomarkers and Drug Targets in PersonalizedCancer PathwaysAlexander Kel, geneXplain GmbHDaily <strong>Program</strong>(W10-2) Pathway Analysis in Expression ProteomicsRoman Zubarev, Chemistry I Division, Department <strong>of</strong> Medical Biochemistry and Biophysics, Karolinska Institute(W10-3) Metabolic Biomarkers, Metabolic Networks, and Pathway AnalysisVladimir Tolstikov, University <strong>of</strong> California Davis Genome Center6:00 pm – 7:00 pm CAC Hosted <strong>ABRF</strong>-Vendor Interface Meeting — Level 1, Exhibit Ballroom C7:00 pm – 8:00 pm Core Administrators Network – Coordinating Committee (CAN-CC) Meeting — Level 1, Exhibit Ballroom C7:30 pm – 9:00 pm Vendor PresentationsSee page 120 for detailed information.8:00 pm – 11:00 pm (W15a) ETD Workshop Seminar Series PART I: Manual Interpretation <strong>of</strong> Electron Transfer Dissociation (ETD)Mass Spectra <strong>of</strong> Peptides* — Level 2, Grand Oaks Ballroom N/OPresenter: Donald F. Hunt, Departments <strong>of</strong> Chemistry and Pathology, University <strong>of</strong> VirginiaTuesday, February 22*Attendees must be registered for <strong>ABRF</strong> <strong>2011</strong> to attend the workshop and must also complete the ETD Workshop SeminarForm. Please visit the Registration Desk to sign up for the session.7:00 am – 6:00 pm Registration Open — Level 2, Ballroom Level Registration Desk7:00 am – 7:45 am Continental Breakfast — Level 1, Exhibit Ballroom Foyer7:45 am – 8:50 am Plenary Session — Level 1, Exhibit Ballroom CDevelopment by Selventa <strong>of</strong> a Therapeutic Diagnosticin Ulcerative ColitisDavid de Graaf, President & CEO, SelventaTMStratification Biomarker for Drug Response<strong>ABRF</strong> <strong>2011</strong> — Technologies to Enable Personalized Medicine • 23
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Illumina Genome Analyzer. PicoPlex
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uniformity, reproducibility of enri
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kits for Tempus TM and PAXgene® st
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165 Benchmarking miRNA ExpressionLe
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Phoenix crystallography robot and a
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Laboratory is located next door and
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data of a Thermo Orbitrap instrumen
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**197 Multi-Functional Superparamag
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pattern of N-linked glycans in form
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advantage of using two separate 15
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allowed absolute quantitation. Comp
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levels between the animal groups. A
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MuDPIT, and off-gel electrophoresis
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237 Multi-Site Assessment of Proteo
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with good limits of quantification
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249 Rapid Monoclonal Antibody Glyca
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OOng, J. - 117PPatel, S. - 169Peake
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AnaSpec, Eurogentec Group Booth 417
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FASEB MARC Program Booth 4169650 Ro
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IntegenX, Inc. Booth 2015720 Stoner
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Nonlinear Dynamics Booth 1052530 Me
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Roche Applied Science Booth 5009115
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Exhibit Hall FloorplanGrand Oaks Ba
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Exhibitor List in Booth OrderExhibi
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This workshop will present ways to
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Grand Oaks Ballroom,Rooms P&Q, Leve
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NotesNotesABRF 2011 — Technologie
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Tuesday, February 22 — 12:00 pm -
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MARCH 16-20, 2012 • DISNEY’S CO