Annual Report - IHBT

CSIR-IHBT Annual Report 2010-11HAWTHORN (Crataegus oxyacantha)The plant is a valuable remedy for cardiovascular system. Its leaves and fruits are rich sources ofpolyphenolic compounds which are responsible for hypolipidemic, antioxidant, anti-inflammatory,hypotensive and anti-ischemic activities. In characterization of the active principles, 10 moleculesof flavonoids, triterpenoids, steroidal and phenolic skeletons were isolated from n-butanol andethyl acetate fractions (Fig. 26). A method was also developed and validated to determine mainphenolic compounds viz., chlorogenic acid, epicatechin, vitexin, hyperoside, quercetin andapigenin in the plant extracts.Fig. 26 Chemical structures of compounds isolated from C. oxyacantha31