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Guidelines for malaria prevention in travellers from the United ...

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G UIDELINES FOR M ALARIA P REVENTION IN<br />

T RAVELLERS FROM THE U NITED K INGDOM<br />

2.4 Where is <strong>malaria</strong> found?<br />

Figure 2 shows <strong>the</strong> global distribution of<br />

<strong>malaria</strong> as assessed by <strong>the</strong> World Health<br />

Organization (WHO) <strong>in</strong> 2003 2 .<br />

In-country maps of prophylactic advice<br />

l<strong>in</strong>ked to <strong>malaria</strong> distribution are available<br />

<strong>in</strong> <strong>the</strong> web-based version of <strong>the</strong>se<br />

guidel<strong>in</strong>es <strong>for</strong> use when advis<strong>in</strong>g<br />

<strong>in</strong>dividual <strong>travellers</strong>. The likelihood of<br />

<strong>malaria</strong> transmission may vary<br />

considerably with<strong>in</strong> one country.<br />

2.5 Level of risk of exposure to<br />

<strong>malaria</strong> and what affects it<br />

Exposure of <strong>in</strong>dividual <strong>travellers</strong> to<br />

<strong>malaria</strong> is <strong>in</strong>fluenced by <strong>the</strong> number of<br />

<strong>in</strong>fectious bites received. Conditions<br />

affect<strong>in</strong>g number of <strong>in</strong>fectious bites<br />

received are given below.<br />

22<br />

FIGURE 2<br />

Malaria endemicity<br />

Very high<br />

High<br />

Moderate<br />

Low<br />

No <strong>malaria</strong><br />

GLOBAL DISTRIBUTION OF MALARIA AS ASSESSED BY<br />

THE WORLD HEALTH ORGANIZATION IN 2003<br />

Temperature, altitude and season<br />

• The optimum conditions <strong>for</strong> <strong>malaria</strong><br />

transmission are high humidity and an<br />

ambient temperature <strong>in</strong> <strong>the</strong> range 20<br />

to 30°C 3 .<br />

• Malaria transmission does not occur <strong>in</strong><br />

regions with temperatures below <strong>the</strong><br />

16°C iso<strong>the</strong>rm (l<strong>in</strong>e on a wea<strong>the</strong>r<br />

map jo<strong>in</strong><strong>in</strong>g all <strong>the</strong> places that have<br />

<strong>the</strong> same temperature).<br />

• Parasite maturation <strong>in</strong> <strong>the</strong> mosquito<br />

cannot take place at altitudes greater<br />

than 2000 metres.<br />

• Seasonal ra<strong>in</strong>fall <strong>in</strong>creases mosquito<br />

breed<strong>in</strong>g.<br />

Rural versus urban location<br />

• Malaria prevalence is generally higher<br />

<strong>in</strong> rural than <strong>in</strong> urban areas, especially<br />

<strong>in</strong> Africa where <strong>the</strong> <strong>in</strong>tensity of<br />

transmission is on average about 8<br />

times higher <strong>in</strong> villages than towns 4

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