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Guidelines for malaria prevention in travellers from the United ...

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G UIDELINES FOR M ALARIA P REVENTION IN<br />

T RAVELLERS FROM THE U NITED K INGDOM<br />

50<br />

TABLE 12<br />

RISK<br />

Risk high<br />

Marked<br />

chloroqu<strong>in</strong>e<br />

resistance<br />

present<br />

Risk<br />

variable<br />

or high<br />

Chloroqu<strong>in</strong>e<br />

resistance<br />

present<br />

Risk variable<br />

to low<br />

No<br />

chloroqu<strong>in</strong>e<br />

resistance<br />

present<br />

MALARIA CHEMOPROPHYLAXIS IN SOUTH AMERICA<br />

AND CARIBBEAN<br />

COUNTRY<br />

Bolivia (Amazon bas<strong>in</strong> area)<br />

Brazil (Amazon bas<strong>in</strong> (i.e.‘Legal Amazon’<br />

area, see map); elsewhere very low risk<br />

and no chemoprophylaxis)<br />

Colombia (most areas below 800m)<br />

Ecuador (Esmeraldas Prov<strong>in</strong>ce; see below<br />

<strong>for</strong> elsewhere)<br />

French Guiana (especially border areas)<br />

Guyana (all <strong>in</strong>terior regions, lesser risk<br />

at coast)<br />

Peru (Amazon bas<strong>in</strong> area)<br />

Sur<strong>in</strong>ame (except Paramaribo and coast)<br />

Venezuela (all areas south of and <strong>in</strong>clud<strong>in</strong>g<br />

<strong>the</strong> Or<strong>in</strong>oco river; north of <strong>the</strong> river<br />

chloroqu<strong>in</strong>e plus proguanil recommended<br />

see below)<br />

Amazon bas<strong>in</strong> areas of Bolivia and<br />

Venezuela and Peru<br />

Bolivia (rural areas below 2500m)<br />

Ecuador (areas below 1500m; no <strong>malaria</strong><br />

<strong>in</strong> Galapagos Islands nor Guayaquil)<br />

Panama (east of canal, canal zone itself no risk)<br />

Peru (O<strong>the</strong>r rural areas East of <strong>the</strong> Andes<br />

and West of <strong>the</strong> Amazon Bas<strong>in</strong> below<br />

1500m)<br />

Venezuela (north of <strong>the</strong> Or<strong>in</strong>oco river;<br />

Caracas free of <strong>malaria</strong>; south and <strong>in</strong>clud<strong>in</strong>g<br />

Or<strong>in</strong>oco river, risk high see above)<br />

Argent<strong>in</strong>a (rural areas along nor<strong>the</strong>rn<br />

borders only)<br />

Belize (rural except Belize district)<br />

Costa Rica (rural below 500m)<br />

Dom<strong>in</strong>ican Republic<br />

El Salvador (only Santa Ana prov<strong>in</strong>ce <strong>in</strong> west)<br />

Guatemala (below 1500m)<br />

Haiti<br />

Honduras<br />

Mexico (<strong>in</strong> states of Oaxaca & Chiapas)<br />

Nicaragua<br />

Panama (west of canal, canal zone<br />

itself no risk)<br />

Paraguay (some rural areas)<br />

See tables 3-6 <strong>for</strong> details of regimens<br />

ACMP<br />

RECOMMENDED<br />

REGIMEN<br />

Mefloqu<strong>in</strong>e<br />

OR<br />

Doxycycl<strong>in</strong>e<br />

OR<br />

Atovaquone/<br />

Proguanil<br />

Chloroqu<strong>in</strong>e<br />

plus proguanil<br />

Chloroqu<strong>in</strong>e<br />

ALTERNATIVE<br />

REGIMEN IF<br />

RECOMMENDED<br />

REGIMEN<br />

UNSUITABLE<br />

Chloroqu<strong>in</strong>e<br />

plus<br />

proguanil<br />

Mefloqu<strong>in</strong>e<br />

OR<br />

Doxcycl<strong>in</strong>e<br />

OR<br />

Atovaquone/<br />

Proguanil<br />

Proguanil

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