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Guidelines for malaria prevention in travellers from the United ...

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G UIDELINES FOR M ALARIA P REVENTION IN<br />

T RAVELLERS FROM THE U NITED K INGDOM<br />

48<br />

TABLE 10<br />

RISK<br />

Risk high<br />

Widespread<br />

chloroqu<strong>in</strong>e<br />

AND<br />

mefloqu<strong>in</strong>e<br />

resistance<br />

Risk high<br />

Chloroqu<strong>in</strong>e<br />

resistance<br />

common<br />

Risk variable<br />

Some<br />

chloroqu<strong>in</strong>e<br />

resistance<br />

Risk very low<br />

MALARIA CHEMOPROPHYLAXIS IN SOUTH EAST ASIA<br />

COUNTRY<br />

Cambodia (western prov<strong>in</strong>ces)<br />

Thailand (near ma<strong>in</strong>land borders with Cambodia, Laos<br />

and Myanmar; low risk and bite avoidance only Chiang<br />

Rai and Kwai bridge)<br />

Myanmar (eastern part of Shan State)<br />

Cambodia (except no risk <strong>in</strong> Phnom Penh)<br />

Ch<strong>in</strong>a (only <strong>in</strong> Yunnan and Ha<strong>in</strong>an; chloroqu<strong>in</strong>e <strong>in</strong> o<strong>the</strong>r<br />

remote areas of Ch<strong>in</strong>a)<br />

East Timor (= Timor-Leste)<br />

Papua (Irian Jaya) (part of Indonesia)<br />

Laos (except no risk <strong>in</strong> Vientiane)<br />

Lombok (part of Indonesia)<br />

Myanmar (<strong>for</strong>merly Burma [see above <strong>for</strong> Shan State])<br />

Malaysia East (Sabah only except Kota K<strong>in</strong>abalu where<br />

awareness and bite <strong>prevention</strong> advised)<br />

Vietnam (except areas listed below that are low risk)<br />

Indonesia (except Bali and cities where low risk; <strong>for</strong><br />

Papua (Irian Jaya) and Lombok mefloqu<strong>in</strong>e or doxycycl<strong>in</strong>e<br />

or atovaquone-proguanil recommended)<br />

Philipp<strong>in</strong>es (rural below 600m; no risk <strong>in</strong> cities, nor Cebu,<br />

Bohol and Catanduanes)<br />

Malaysia West (pen<strong>in</strong>sular) Inland <strong>for</strong>ested areas (not<br />

Cameron Highlands) and Malaysia East (<strong>in</strong>land <strong>for</strong>ested<br />

areas of Sarawak)<br />

Bali (part of Indonesia)<br />

Brunei<br />

Ch<strong>in</strong>a (ma<strong>in</strong> tourist areas <strong>in</strong>clud<strong>in</strong>g Yangtze cruises)<br />

Hong Kong<br />

Malaysia East (except Sabah (see above) and Sarawak<br />

(chloroqu<strong>in</strong>e plus proguanil)<br />

Malaysia West (low risk <strong>in</strong>clud<strong>in</strong>g Cameron Highlands<br />

except <strong>in</strong>land <strong>for</strong>ested areas where chloroqu<strong>in</strong>e<br />

plus proguanil)<br />

North Korea (a few sou<strong>the</strong>rn areas have limited risk)<br />

South Korea (limited risk <strong>in</strong> extreme Northwest)<br />

S<strong>in</strong>gapore<br />

Thailand (prophylaxis only advised <strong>for</strong> areas listed above)<br />

Vietnam (see above <strong>for</strong> high risk areas; low risk <strong>in</strong> cities,<br />

coast between Ho Chi M<strong>in</strong>h and Hanoi, and <strong>the</strong> Mekong<br />

River until close to <strong>the</strong> Cambodian border)<br />

ACMP<br />

RECOMMENDED<br />

REGIMEN<br />

Doxycycl<strong>in</strong>e<br />

OR<br />

Atovaquone/<br />

Proguanil<br />

Mefloqu<strong>in</strong>e<br />

OR<br />

Doxycycl<strong>in</strong>e<br />

OR<br />

Atovaquone/<br />

Proguanil<br />

Chloroqu<strong>in</strong>e plus<br />

proguanil<br />

Awareness*<br />

See tables 3-6 <strong>for</strong> details of regimens<br />

*Awareness of small risk of <strong>malaria</strong>; avoid mosquito bites and seek medical attention <strong>for</strong><br />

any suspicious symptoms (up to about a year later) but tablets not considered necessary.

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