HIV/AIDS Treatment and Care : Clinical protocols for the European ...

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3 HIV/AIDS TREATMENT AND CARE CLINICAL PROTOCOLS FOR THE WHO EUROPEAN REGION Annex 6. List of antiretroviral drugs 5 Table 1 . Antiretroviral drug list International non-proprietary name(INN) NRTIs Proprietary name Pharmaceutical company Abacavir (ABC) Epzicom US, Kivexa United Kingdom (lamivudine/ abacavir) Trizivir Europe, United Kingdom, US (zidovudine/ lamivudine/abacavir) Ziagen United Kingdom, United States GlaxoSmithKline Abavir Genixpharma Virol Virol LZ (abacavir/lamivudine/zidovudine) Ranbaxy Didanosine (ddI) Videx, Videx EC Bristol-Myers Squibb Dinex EC Odivir Kit (didanosine/lamivudine/efavirenz) Cipla Aviro-Z Virosine Viro-Z Ranbaxy (India) Divir Thai Government Emtricitabine (FTC) ATRIPLA (efavirenz/emtricitabine/tenofovir) Bristol-Myers Squibb and Gilead Sciences Emtriva Truvada (tenovovir/emtricitabine) Gilead Sciences Lamivudine (3TC) Combivir United Kingdom, United States (lamivudine/zidovudine) Epivir United Kingdom, United States, Zeffix United Kingdom Epzicom United States, Kivexa United Kingdom (lamivudine/abacavir) Trizivir United Kingdom, United States (zidovudine/ lamivudine/abacavir) GlaxoSmithKline Lamivox Stavex-L (lamivudine/stavudine) Stavex-LN (lamivudine/nevirapine/stavudine) Zidovex-L (lamivudine/zidovudine) Zidovex-LN (lamivudine/nevirapine/zidovudine) Aurobindo Duovir (lamivudine/zidovudine) Duovir-N (lamivudine/nevirapine/zidovudine) Lamivir Odivir Kit (didanosine/lamivudine/efavirenz) Triomune (lamivudine/nevirapine/stavudine) Cipla Heptavir Lamistar 30, Lamistar 40 (lamivudine/stavudine) Nevilast (lamivudine/nevirapine/stavudine) Zidolam (lamivudine/zidovudine) Genixpharma Virolam Virocomb (lamivudine/zidovudine) Virolans (lamivudine/nevirapine/stavudine) Virolis (lamivudine/stavudine) Virol LZ, Abac-ALZ (abacavir/lamivudine/ zidovudine) Ranbaxy 5 This list is a compilation of those ARVs that are widely used, and should not be construed to be exhaustive. It was accurate as of 31 July 2006. Disclaimer: The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned.
PATIENT EVALUATION AND ANTIRETROVIRAL TREATMENT FOR ADULTS AND ADOLESCENTS International non-proprietary name(INN) Proprietary name Pharmaceutical company Stavudine (d4T) Zerit, Zerit XR Bristol-Myers Squibb Stavex Stavex-L (lamivudine/stavudine) Stavex-LN (lamivudine/nevirapine/stavudine) Aurobindo Stavir Cipla Lamivir-S (lamivudine/stavudine) Triomune (lamivudine/nevirapine/stavudine) Lamistar (lamivudine/stavudine) Genixpharma Nevilast (lamivudine/nevirapine/stavudine) Stag Stavir GPO (Thailand) Avostav Triviro-LNS (lamivudine/nevirapine/stavudine) Virolans (lamivudine/nevirapine/stavudine) Virolis, Coviro (lamivudine/stavudine) Virostav Ranbaxy Tenofovir (TDF) Truvada (tenofovir/emtricitabine) Viread (tenofovir) Gilead Sciences ATRIPLA (efavirenz/emtricitabine/tenofovir) Bristol-Myers Squibb Triple nuceoside (TRZ) Trizivir United Kingdom, United States (zidovudine/ lamivudine/abacavir) GlaxoSmithKline Zidovudine (ZDV or AZT) Combivir United Kingdom, United States (lamivudine/zidovudine) Retrovir United Kingdom, United States Trizivir United Kingdom, United States (zidovudine/ lamivudine/abacavir) GlaxoSmithKline Zidovex Auribindo NNRTIs Zidovir Duovir (lamivudine/zidovudine) Cipla Zido-H (zidovudine) Genixpharma Antivir GPO (Thailand) Aviro-Z Virocomb (lamivudine/zidovudine) Virol LZ (abacavir/lamivudine/zidovudine) Viro-Z Ranbaxy Delavirdine (DLV) Rescriptor Pfizer, Inc. Efavirenz (EFV) Sustiva Europe, United Kingdom, Stocrin Australia, Europe, Latin America, South Africa ATRIPLA (efavirenz/emtricitabine/tenofovir) Bristol-Myers Squibb Viranz Aurobindo Efavir Cipla Estiva Genixpharma Efferven Ranbaxy 3
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Page 5 and 6: iv Acknowledgements The editors wou
Page 7 and 8: vi Marco Vitoria (WHO headquarters)
Page 9 and 10: viii CRP C-reactive protein CS caes
Page 11 and 12: x LFT liver function test LGE linea
Page 13 and 14: xii TDM therapeutic drug monitoring
Page 15 and 16: xiv Introduction HIV is a chronic i
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Page 20 and 21: Annex 7. Glossary .................
Page 22 and 23: HIV/AIDS TREATMENT AND CARE CLINICA
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palliative care for people living w
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III. Initial evaluation palliative
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IV. Treatment palliative care for p
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Fig. 2. who analgesic ladder for ma
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Type of pain or treatment Usual sta
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Table 5. prevalence of symptoms in
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Type Symptoms Possible causes Disea
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Type Symptoms Possible causes Disea
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Table 22. Management of mania and B
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V. Special advice for terminal care
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Table 27. common manifestations in
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References palliative care for peop
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VI. Suggested minimum data to be co
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Contents I. Policy and principles .
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I. Policy and principles HIV/AIDS T
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HIV/AIDS TREATMENT AND CARE FOR INJ
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° bacterial pneumonia ° endocardi
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Social factors are: • homelessnes
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Table 3. Interactions between ARV d
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Other medications Use Rifampicin (R
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Table 5. Interactions of illicit dr
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ANNEX 1 ASI6 C © 2004 University o
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• Cardiovascular Hypertension Tac
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Contents I. Epidemiology and natura
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ManageMent of Hepatitis C and HiV C
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Annex 3. Alcohol screening question
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Table 16. a sample of the drug pipe
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3.2. Considerations regarding treat
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I. Prevention strategies Prevention
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Prevention of HePatitis a, B, C and
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Prevention of HePatitis a, B, C and
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5. Contraceptive methods for women
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I. Policy issues Prevention of Hiv
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III. Initial evaluation Prevention
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Prevention of Hiv transmission from
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6. Fungal infections...............
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• Disseminated non-tuberculous my
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Annex 3. Rabies vaccines ..........
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442 hIv/aIds tReatment and caRe clI
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Contents I. Policy issues .........
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I. Policy issues post-exposure prop
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post-exposure prophylaxis for hiv i
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° condom use ° presence of STIs (
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Table 3. thre- drug arv regimens Pr
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VI. Suggested minimum data to be co
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History of antiretroviral treatment
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Test results: HBV: HCV: HIV: Post-t
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Infection control standard precauti
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The World Health Organization (WHO)
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