Annual-Report-2019

HOST LABORATORIES IN
LIFE & HEALTH SCIENCES
BIOMOLÉCULES ET BIOTECHNOLOGIES VÉGÉTALES (BBV)
EA 2106 - UNIVERSITÉ DE TOURS
the Lab of Plant Biomolecules and Biotechnology (BBV-EA2106, Tours University),
founded in 1987 and located at the Faculty of Pharmacy. This Lab is mainly dedicated to
the characterization of plant specialized metabolisms and their use as pharmaceuticals,
cosmeceuticals and biopesticides with the use of combinatory approaches in plant physiology, molecular
biology, biochemistry, bioinformatic (identification of genes), genetic and metabolomics. The lab is also
involved in the development of plant biotechnologies (in vitro technologies and GMOs) and in bio engineering
(production of plant metabolites in yeast).These two laboratories also work on applied research programs to
identify new natural preservatives or Biologically active ingredients (BAIs) for cosmetics.
BIOLOGIE DES OISEAUX ET AVICULTURE (BOA)
UMR 0083 - CENTRE INRAE VAL DE LOIRE, UNIVERSITÉ DE TOURS
In 2018, the INRA URA unit became the UMR BOA, Avian Biology & Poultry Research, in
collaboration with the University of Tours. In the context of its mandate, UMR BOA conducts
integrated research on the biology of birds, from the molecular level to that of the entire
animal in its environment. The overall objective is to produce knowledge in the fields of physiology and genetics
and to contribute to the development of sustainable livestock systems. Their research is based on three axes
shared by the four teams of the unit: To characterise the physiological, molecular, and genetic mechanisms
underlying the biological functions of birds (metabolism, growth and development, digestion, plasticity, egg
formation and function); To propose evaluation tools, by developing indicators or biomarkers that can be used
in selection programs and during rearing to improve bird adaptability and the quality of products (eggs and
meat); To integrate knowledge and tools so as to contribute to the transition from animal husbandry systems
to multi-performance and to the food and non-food valuation of poultry products.
CENTRE DE BIOPHYSIQUE MOLÉCULAIRE (CBM)
UPR 4301 - CNRS
CBM is one of the largest research laboratories in the region Centre-Val de Loire. It was founded in 1967
to set up interdisciplinary collaboration between chemists, biologists and physicists. Researchers at the
CBM are investigating the structure, dynamics and interactions of biomacromolecules. This approach
entails searching for the molecular causes of biological dysfunctions which trigger the development of
diseases. The center is also recognized for its research in biomedical imaging. One key goal of CBM is to conceive new
strategies in human therapy by combining innovative approaches in peptide/protein synthesis, biochemistry, bio-physics,
molecular and computational biology. For this purpose, biomolecular interactions involving DNA, RNA, proteins and ligand
are studied at the atomic and molecular level. Moreover, some research projects are dedicated to the identification of new
therapeutic targets and the development of innovative delivery systems for therapeutic and imaging agents in various
pathologies. Novel therapeutic strategies are developed using original nucleic acid delivery systems that combine chemical
vectors and physical methods. One main area is the optimization of innovative vaccination based on messenger RNA coding
for tumoral or viral antigens for cancer and viral infection, respectively.
Life & Health Sciences 2019
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