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Annual-Report-2019

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HOST LABORATORIES IN

LIFE & HEALTH SCIENCES

INFECTIOLOGIE ANIMALE ET SANTÉ PUBLIQUE (ISP) - UMR

1282 - CENTRE INRAE VAL DE LOIRE, UNIVERSITÉ DE TOURS

The Multi-resistance and Pathogenicity of Nematodes team (MPN) belonging to Infectiology and Public Health Unit (ISP,

UMR 1282). The main aim of the MPN team is the sustainable control of gastro-intestinal parasitic nematodes (GIN) in

livestock. During the past ten years, they have investigated several different aspects of anthelmintic resistance, from

field studies to molecular characterisation of parasite anthelmintic targets. The team identified the first molecular

markers for levamisole resistance, and was the first to perform the functional expression of strongylid AChR in Xenopus

oocytes. The range of expertise includes: molecular ecology, mathematical modelling, biochemistry and cellular and

molecular biology. They have participated in numerous international projects dealing with anthelmintic resistance.

LABORATOIRE DE BIOLOGIE DES LIGNEUX ET DES GRANDES

CULTURES (LBLGC) - EA 1207 - UNIVERSITÉ D’ORLÉANS,

CENTRE INRAE VAL DE LOIRE

The Laboratory of Woody Plants and Crops Biology UPRES EA1207 was created under this label

in January, 2000. This day, it is constituted of 4 research teams called respectively: Trees and

Responses to Hydric and Environmental Constraints, Entomology and Integrated Biology, Cell

Signaling and Plants Lignans, this last team being located in the Scientific Campus of Chartres.

Founded in 1996, the team Plant Lignans works in the fields of plant physiology, molecular biology (gene function),

biochemistry (biosynthesis of molecules through the plant), analytical chemistry and in vitro culture applied to the study

of phenylpropanoids derived products. This team is also working on applied research programmes to find new natural

preservatives or active ingredients for cosmetics. More recently the team started to work on allelopathic activities of

plant specialised metabolites.

Life & Health Sciences 2019

NANOMÉDICAMENTS ET NANOSONDES (NMNS)

EA 6295 - UNIVERSITÉ DE TOURS

The NMNS group is part of the Philippe Maupas Faculty of Pharmacy of the Université de

Tours. It is lead by Professor Igor Chourpa. It started in 2008 and became an independent

“Equipe d’Accueil” in 2012. Its scientific research centers around the development of

nanotechnologies for anticancer drugs and/or contrast agents for imaging with applications in cancer theranostics as

well as dermatological and cosmetic science. The group’s activities combine expertise in biology, chemistry (synthetic

and analytical) and physics. This confluence of expertises is reflected in the pluridisciplinarity of its staff, consisting

of pharmaceutical scientists, chemists and physicists. The group enjoys research collaborations within an extensive

national and international network consisting of academic and industrial partners. Funding sources include the Région

Centre, La Ligue contre le Cancer, the Institut National du Cancer, ERA.NET Plus and ARD 2020 CosmétoSciences / LE

STUDIUM.

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