Annual-Report-2019
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HOST LABORATORIES IN
LIFE & HEALTH SCIENCES
INFECTIOLOGIE ANIMALE ET SANTÉ PUBLIQUE (ISP) - UMR
1282 - CENTRE INRAE VAL DE LOIRE, UNIVERSITÉ DE TOURS
The Multi-resistance and Pathogenicity of Nematodes team (MPN) belonging to Infectiology and Public Health Unit (ISP,
UMR 1282). The main aim of the MPN team is the sustainable control of gastro-intestinal parasitic nematodes (GIN) in
livestock. During the past ten years, they have investigated several different aspects of anthelmintic resistance, from
field studies to molecular characterisation of parasite anthelmintic targets. The team identified the first molecular
markers for levamisole resistance, and was the first to perform the functional expression of strongylid AChR in Xenopus
oocytes. The range of expertise includes: molecular ecology, mathematical modelling, biochemistry and cellular and
molecular biology. They have participated in numerous international projects dealing with anthelmintic resistance.
LABORATOIRE DE BIOLOGIE DES LIGNEUX ET DES GRANDES
CULTURES (LBLGC) - EA 1207 - UNIVERSITÉ D’ORLÉANS,
CENTRE INRAE VAL DE LOIRE
The Laboratory of Woody Plants and Crops Biology UPRES EA1207 was created under this label
in January, 2000. This day, it is constituted of 4 research teams called respectively: Trees and
Responses to Hydric and Environmental Constraints, Entomology and Integrated Biology, Cell
Signaling and Plants Lignans, this last team being located in the Scientific Campus of Chartres.
Founded in 1996, the team Plant Lignans works in the fields of plant physiology, molecular biology (gene function),
biochemistry (biosynthesis of molecules through the plant), analytical chemistry and in vitro culture applied to the study
of phenylpropanoids derived products. This team is also working on applied research programmes to find new natural
preservatives or active ingredients for cosmetics. More recently the team started to work on allelopathic activities of
plant specialised metabolites.
Life & Health Sciences 2019
NANOMÉDICAMENTS ET NANOSONDES (NMNS)
EA 6295 - UNIVERSITÉ DE TOURS
The NMNS group is part of the Philippe Maupas Faculty of Pharmacy of the Université de
Tours. It is lead by Professor Igor Chourpa. It started in 2008 and became an independent
“Equipe d’Accueil” in 2012. Its scientific research centers around the development of
nanotechnologies for anticancer drugs and/or contrast agents for imaging with applications in cancer theranostics as
well as dermatological and cosmetic science. The group’s activities combine expertise in biology, chemistry (synthetic
and analytical) and physics. This confluence of expertises is reflected in the pluridisciplinarity of its staff, consisting
of pharmaceutical scientists, chemists and physicists. The group enjoys research collaborations within an extensive
national and international network consisting of academic and industrial partners. Funding sources include the Région
Centre, La Ligue contre le Cancer, the Institut National du Cancer, ERA.NET Plus and ARD 2020 CosmétoSciences / LE
STUDIUM.
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