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Annual-Report-2019

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PARTNERS

Dr William Brackenbury

University of York - UK

Dr Juan-Carlos Gomora

National Autonomous University of

Mexico - MX

Prof. Timothy G. Hales

University of Dundee - UK

Prof. Sadanandan Velu

University of Alabama in

Birmingham - USA

AROUND THE PROJECT

Oral communications

Posters

. S. ROGER - iPSCs: From Disease Models to Mini-Organs, Tours, France. “Role of ion

channels in cancer cell invasiveness, mammary tumour growth and metastatic progression”

(29 January 2019)

. S. ROGER: UTL – Université du temps libre, Université de Tours: «Electricité cellulaire et

développement des cancers : vers de nouvelles stratégies de traitements » (05 Feb 2019)

. S. ROGER: Declics 2019 – Dialogues entre chercheurs et Lycéens pour les intéresser à la

Construction des Savoirs (04 Dec 2019) : « La recherche biomédicale, exemple du projet sur

l’électricité cellulaire dans l’invasion cancéreuse et le développement des métastases ».

. O LOPEZ-CHARCAS, S Dutta, W Brouillette, S Roger and S E. Velu Biophysical

characterization of new small-molecule blockers of nNaV1.5 channels expressed in breast

cancer cells. 30th Ion channel meeting. Sètes, FR (8-11 Sept 2019)

. Lucile Poisson, Osbaldo Lopez Charcas, Widad Lahlou, Adrien Petereau, Emiliane

Taillebois, Adélaïde Doray, Mehdi Ouaissi, Sébastien Roger, Pierre Besson and Driffa Moussata.

Expression of pore-forming and auxiliary subunits of voltage-gated sodium channels (NaV)

in colorectal cancer, roles in pH regulation and invasive properties. 30th Ion channel meeting.

Sètes, FR (8-11 Sept 2019)

. Adélaïde Doray, Lucie Brisson, Stéphanie Chadet, Lucile Poisson, Osbaldo Lopez Charcas,

Caroline Goupille, Lobna Ouldamer, Christophe Baron, Pierre Besson, Sébastien Roger.

The role of the auxiliary NaVβ4 subunit in maintaining epithelial phenotype. 30th Ion channel

meeting. Sètes, FR (8-11 Sept 2019).

. Adélaïde Doray, Lucie Brisson, Stéphanie Chadet, Lucile Poisson, Osbaldo Lopez Charcas,

Caroline Goupille, Lobna Ouldamer, Christophe Baron, Pierre Besson, Sébastien Roger.

The role of the auxiliary NaVβ4 subunit in maintaining epithelial phenotype. 32nd Colloque

Biotechnocentre, FR (10-11 Oct 2019). Best poster award.

Scientific publications

. Adélaïde Doray, Lucie Brisson, Stéphanie Chadet, Lucile Poisson, Osbaldo Lopez Charcas,

Caroline Goupille, Lobna Ouldamer, Christophe Baron, Pierre Besson, Sébastien Roger. The

role of the auxiliary NaVβ4 subunit in maintaining epithelial phenotype. Journée recherche

Biomédicale 2019, Facultés de médecine de Tours et d’Angers (13 Dec 2019).

. ROGER S. Na+ /H+ exchanger type-1: a shepherd for cellular transhumance. J Physiol. 2019

Feb;597(3):661-662.

. AUZOUX J, BOSCHETTI G, ANON B, AUBOURG A, CAULET M, POISSON L, BESSON P,

LECOMTE T, ROGER S, PICON L, NANCEY S, MOUSSATA D, FLOURIE B. Usefulness of confocal

laser endomicroscopy for predicting postoperative recurrence in patients with Crohn’s disease: a

pilot study. Gastrointest Endosc. 2019 Jul;90(1):151-157.

. GRADEK F., LOPEZ-CHARCAS O., CHADET S., POISSON L., OULDAMER L., GOUPILLE

C., JOURDAN M.-L., CHEVALIER S., MOUSSATA D., BESSON P. & ROGER S. Sodium channel

NaV1.5 controls epithelial-to-mesenchymal transition and invasiveness in breast cancer cells

through its regulation by the salt-inducible kinase-1. Scientific reports. 2019 Dec 9;9(1):18652.

Life & Health Sciences 2019

65

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