2005-06 - Office of the Registrar - Duke University

University Programs: Cell and Molecular Biology, Genetics, the Medical Scientist Training
Program, and the Developmental Biology Training Program.
The Department of Immunology has outstanding facilities for carrying out all aspects
of immunologic research. A description of the Ph.D. program, prerequisites for admission,
and research in the department may be found at http://immunology.mc.duke.edu or by
emailing dgs-immunology@duke.edu.
209. Independent Study. A laboratory or library project. Consent of director of undergraduate
studies and instructor required. Instructor: Staff. Variable credit.
213S. Computational Immunology and Immunegenomics. 3 units. C-L: see
Bioinformatics & Genome Technology 213S
244. Principles of Immunology. An introduction to the molecular and cellular basis of the
immune response. Topics include anatomy of the lymphoid system, lymphocyte biology,
antigen-antibody interactions, humoral and cellular effector mechanisms, and control of
immune responses. Prerequisites: Biology 119 and Chemistry 151L or equivalents.
Instructors: Dawson and staff. 3 units. C-L: Biology 244
252. Virology. Molecular biology of mammalian viruses, with emphasis on mechanisms of
virus replication, virus-host interactions, viral pathogenicity, and the relationship of virus
infection to neoplasia. Consent of instructor required. Instructor: Keene and staff. 3 units.
258. Structural Biochemistry I. 2 units. C-L: see Biochemistry 258; also C-L: Cell and
Molecular Biology 258, Cell Biology 258, University Program in Genetics 258, Molecular
Biophysics 258
259. Structural Biochemistry II. 2 units. C-L: see Biochemistry 259; also C-L: Cell
Biology 259, Molecular Biophysics 259, University Program in Genetics 259
268. Biochemical Genetics II: From RNA to Protein. 2 units. C-L: see Biochemistry 268;
also C-L: Cell Biology 268, University Program in Genetics 268
291. Comprehensive Immunology. An intensive course in the biology of the immune
system and the structure and function of its component parts. Major topics discussed are:
properties of antigens; specificity of antibody molecules and their biologic functions; cells
and organs of the lymphoid system; structure and function of complement; inflammation and
nonspecific effector mechanisms; cellular interactions and soluble mediators in lymphocyte
activation, replication, and differentiation; regulation of immune responses; molecular
structure and genetic organization of immunoglobulins, histocompatibility antigens, and Tcell
receptor. Required course for all students specializing in immunology. Consent of
instructor required. Prerequisite: recommended, Immunology 244 or equivalent. Instructor:
Krangel and staff. 3 units.
300. Tumor Immunology. An advanced seminar based on original literature focusing on
neoplasia and the immune system. Topics include a general introduction to malignancy and
immune responses associated with them, regulation of the immune response to tumor,
vaccine development, the role of gene therapy, the use of tumor-reactive monoclonal
antibodies, and characteristics of tumor antigens. Prerequisite: Immunology 291. Instructor:
Tedder and staff. 2 units.
332. Immunology Seminar. Work in progress seminar in which students and postdoctoral
trainees give 30min-1 hour presentations of their research. Considered a showcase of current
research in the Department of Immunology. All students enrolled in Immunol programs are
required to give a presentation once per year. Informal questions and discussion are
encouraged throughout presentation. First- and second-year Immunology graduate students
should register for Section 1 for graded credit. Immunology students beyond the second year
should register for Section 2 for non-graded credit. Students of non-Immunology majors
should register for Section 2 or get permission from course director for Section 1. Attendance
is essential for both sections. Director: Zhuang. 1 unit.
335. Current Topics in Immunology. Focus on current immunology research,
emphasizing emerging research areas and new directions in established areas. Students
Immunology (IMMUNOL) 181