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2005-06 - Office of the Registrar - Duke University

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347. Seminar in Toxicology. A weekly research seminar throughout <strong>the</strong> year is required <strong>of</strong><br />

participants in <strong>the</strong> Toxicology Program. Students, faculty, and invited speakers present <strong>the</strong>ir<br />

findings. Instructor: Levin. 1 unit.<br />

348. Seminar in Toxicology. A weekly research seminar throughout <strong>the</strong> year is required <strong>of</strong><br />

participants in <strong>the</strong> Toxicology Program. Students, faculty, and invited speakers present <strong>the</strong>ir<br />

findings. Instructor: Levin. 1 unit.<br />

360. Neuropharmacology: From Molecules to Behavior. Seminar-lecture course<br />

emphasizing neurotransmitter mechanisms and <strong>the</strong> mechanisms <strong>of</strong> action <strong>of</strong> drugs used to<br />

modify nervous system function. Material will be drawn from recent literature. Consent <strong>of</strong><br />

instructor required. Instructor: Staff. 3 units. C-L: Neurobiology 360<br />

364. Neurotoxicology. Adverse effects <strong>of</strong> drugs and toxicants on <strong>the</strong> central and peripheral<br />

nervous system; target sites and pathophysiological aspects <strong>of</strong> neurotoxicity; factors<br />

affecting neurotoxicity, screening and assessment <strong>of</strong> neurotoxicity in humans; experimental<br />

methodology for detection and screening <strong>of</strong> chemicals for neurotoxicity. Instructor: Abou-<br />

Donia and staff. 3 units. C-L: Neurobiology 364<br />

417. Cellular Signaling. Mechanism <strong>of</strong> action <strong>of</strong> hormones at <strong>the</strong> cellular level including<br />

hormone-receptor interactions, secondary messenger systems for hormones, mechanisms <strong>of</strong><br />

regulation <strong>of</strong> hormone responsiveness, regulation <strong>of</strong> growth, differentiation and proliferation,<br />

mechanisms <strong>of</strong> transport and ion channels, stimulus sensing and transduction. Some<br />

lectures stress <strong>the</strong> clinical correlation <strong>of</strong> <strong>the</strong> basic course concepts. Instructor: Caron, Casey,<br />

Means, and invited lecturers. 3 units. C-L: Biochemistry 417, Cell Biology 417, Molecular<br />

Cancer Biology 417<br />

418. Molecular Mechanisms <strong>of</strong> Oncogenesis. Lectures, oral presentations, and discussions<br />

on advanced topics and recent advances in <strong>the</strong> molecular biology <strong>of</strong> cancer. Particular<br />

emphasis on strategies to exploit this information in <strong>the</strong> design <strong>of</strong> intervention strategies to<br />

selectively block <strong>the</strong> growth <strong>of</strong> cancer cells. Prerequisite: Cell Biology 417. Instructor:<br />

Counter and staff. 2 units. C-L: Molecular Cancer Biology 418<br />

423. Neurobiological Basis <strong>of</strong> Behavior. Survey <strong>of</strong> neuroanatomical, neurophysiological,<br />

neurochemical, and neuropharmacological evidence <strong>of</strong> central nervous system function as<br />

it relates to normal and abnormal behavior. Clinical description, measurement <strong>of</strong> function,<br />

as well as <strong>the</strong> biological substrates <strong>of</strong> affective disorders and psychoses will be emphasized.<br />

Scientific bases <strong>of</strong> current <strong>the</strong>rapeutic procedures, especially psychopharmacological, will<br />

be examined. Prerequisite: familiarity with basic neuroanatomy, neurophysiology, and<br />

neuropharmacology is assumed. Instructor: Ellinwood and staff. 4 units.<br />

Philosophy (PHIL)<br />

Pr<strong>of</strong>essor Brandon, Chair (201 West <strong>Duke</strong>); Pr<strong>of</strong>essor Schmaltz, Director <strong>of</strong> Graduate<br />

Studies; Pr<strong>of</strong>essors Buchanan, Flanagan, Gillespie (political science), Golding, Grant<br />

(political science), Mahoney, Purves (neurobiology), Rosenberg, Sanford, and Wong;<br />

Associate Pr<strong>of</strong>essors Ferejohn, Güzeldere, and McShea (biology); Assistant Pr<strong>of</strong>essors<br />

Einheuser, Janiak, and Sterrett; Pr<strong>of</strong>essors Emeriti Peach and Welsh; Associate Pr<strong>of</strong>essor <strong>of</strong><br />

<strong>the</strong> Practice Kiss (political science); Adjunct Associate Pr<strong>of</strong>essor Ward; Senior Research<br />

Pr<strong>of</strong>essor Dretske<br />

The Department <strong>of</strong> Philosophy <strong>of</strong>fers graduate work leading to <strong>the</strong> A.M. and Ph.D.<br />

degrees. Tutorial work complements formal instruction. Students may, after taking a<br />

balanced program, specialize in any <strong>of</strong> <strong>the</strong> following fields: <strong>the</strong> history <strong>of</strong> philosophy, logic,<br />

philosophy <strong>of</strong> science, epistemology, metaphysics, philosophy <strong>of</strong> mind, philosophical<br />

analysis, ethics, aes<strong>the</strong>tics, political philosophy, philosophy <strong>of</strong> law, philosophy <strong>of</strong> medicine,<br />

and philosophy <strong>of</strong> religion.<br />

Individual programs <strong>of</strong> study are developed for each student. Prior to being admitted to<br />

candidacy for <strong>the</strong> Ph.D. degree, <strong>the</strong> student must successfully complete seventeen courses<br />

distributed among five subject areas and pass qualifying exams in <strong>the</strong> history <strong>of</strong> philosophy<br />

Philosophy (PHIL) 217

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