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2005-06 - Office of the Registrar - Duke University

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<strong>of</strong>fered at UNC-CH, "Animal Societies and Communication." Prerequisite: Biology 166 or<br />

equivalent. Instructor: Nowicki. 3 units.<br />

277S. Foundations <strong>of</strong> Behavioral Ecology. Readings on behavioral ecology, both<br />

historical papers and papers from <strong>the</strong> current literature that represent <strong>the</strong> most vital areas <strong>of</strong><br />

research in <strong>the</strong> discipline. Instructors: Alberts and Nowicki. 3 units.<br />

278S. Genetic Basis <strong>of</strong> Behavior. The relationship between genotype and behavioral<br />

phenotype. Readings from <strong>the</strong> primary literature, including papers on humans, lab mice, and<br />

wild animal populations. Exploration <strong>of</strong> two philosophical topics: <strong>the</strong> question <strong>of</strong> causality<br />

in <strong>the</strong> natural world and <strong>the</strong> question <strong>of</strong> determinism in biology. Short research paper<br />

required. Instructor: Alberts. 3 units.<br />

279S. Developmental Biology Colloquium. Lectures, seminars, and discussion <strong>of</strong> current<br />

topics in developmental biology. Prerequisites: Biology 118 and/or 119 or equivalent.<br />

Instructor: McClay. 3 units.<br />

280S. Genetic Engineering and Biotechnology. Applications <strong>of</strong> recombinant DNA in<br />

medicine and in agriculture. Topics include diagnosis <strong>of</strong> genetic diseases, gene <strong>the</strong>rapy,<br />

drugs for AIDS and cancer, DNA fingerprinting, cloning <strong>of</strong> mammals, phytoremediation,<br />

crop improvement, and pharmaceutical protein production in transgenic plants and animals.<br />

Social and environmental impacts <strong>of</strong> biotechnology. Prerequisites: Biology 118 and 119 or<br />

consent <strong>of</strong> instructor. Instructor: Sun. 3 units.<br />

281. DNA, Chromosomes, and History. Past and present research on evolution, genetics,<br />

and chromosome biology. The curious path to our present understanding <strong>of</strong> inheritance<br />

including how genes got put on chromosomes and <strong>the</strong> fluctuating fortunes <strong>of</strong> DNA.<br />

Implications <strong>of</strong> current research on chromosome and genome organization for evolutionary<br />

biology. Prerequisite: an introductory course in genetics or cell or molecular biology, or<br />

consent <strong>of</strong> instructor. Instructor: Nicklas. 3 units.<br />

282. Mechanisms <strong>of</strong> Development/Developmental Genetics. 2 units. C-L: see Cell<br />

Biology 282<br />

283. Developmental Genetics. 2 units. C-L: see Cell Biology 283<br />

284. Molecular Population Genetics. Genetic mechanisms <strong>of</strong> evolutionary change at <strong>the</strong><br />

DNA sequence level. Models <strong>of</strong> nucleotide and amino acid substitution; linkage disequilibrium<br />

and joint evolution <strong>of</strong> multiple loci; analysis <strong>of</strong> evolutionary processes, including<br />

neutrality, adaptive selection, and hitchhiking; hypo<strong>the</strong>sis testing in molecular evolution;<br />

estimation <strong>of</strong> evolutionary parameters; case histories <strong>of</strong> molecular evolution. For graduate<br />

students and undergraduates with interests in genetics, evolution, or ma<strong>the</strong>matics.<br />

Instructor: Uyenoyama. 3 units.<br />

286. Evolutionary Mechanisms. Population ecology and population genetics <strong>of</strong> plants and<br />

animals. Fitness concepts, life history evolution, mating systems, genetic divergence, and<br />

causes and maintenance <strong>of</strong> genetic diversity. Prerequisites: Biology 25L and 120 or<br />

equivalents. Instructors: Rausher and Uyenoyama. 3 units.<br />

287S. Macroevolution. Evolutionary patterns and processes at and above <strong>the</strong> species level;<br />

species concepts, speciation, diversification, extinction, ontogeny and phylogeny, rates <strong>of</strong><br />

evolution, and alternative explanations for adaptation and evolutionary trends. Prerequisite:<br />

Biology 25L, 26L, or o<strong>the</strong>r course in plant or animal diversity; recommended, Biology 120<br />

or equivalent. Instructor: Roth. 3 units. C-L: Biological Anthropology and Anatomy 287S<br />

288. Ma<strong>the</strong>matical Population Genetics. Principles <strong>of</strong> formulation and analysis <strong>of</strong><br />

dynamic ma<strong>the</strong>matical models <strong>of</strong> genetic evolution. Rotating topics include: mating<br />

systems, sex ratio, stochastic processes. Prerequisites: calculus; statistics and linear algebra<br />

recommended. Instructor: Uyenoyama. 3 units.<br />

292. Population Ecology. Explores key questions in population ecology from a <strong>the</strong>oretical<br />

perspective. Topics include demography and dynamics <strong>of</strong> structured populations, stochastic<br />

population dynamics, and life history characteristics. Prerequisites: Biology 110L or 112<br />

and consent <strong>of</strong> instructor. Instructors: Morris and Wilson. 3 units.<br />

84 Courses and Academic Programs

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