Survey and health assessment of cosmetic products ... - Miljøstyrelsen

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The Danish Environmental Protection Agency will, when opportunity offers, publish reports and contributions relating to environmental research and development projects financed via the Danish EPA. Please note that publication does not signify that the contents of the reports necessarily reflect the views of the Danish EPA. The reports are, however, published because the Danish EPA finds that the studies represent a valuable contribution to the debate on environmental policy in Denmark.
Contents PREFACE 7 SUMMARY AND CONCLUSIONS 9 BACKGROUND AND PURPOSE 9 THE SURVEY 9 PROJECT RESULTS 10 The investigated products 10 Content of ingredients with antibacterial/antimicrobial properties 10 Chemical analysis 11 Health and risk assessment 12 MAIN CONCLUSIONS 12 1 INTRODUCTION 15 1.1 BACKGROUND 15 1.2 PURPOSE 16 2 DEFINITIONS 17 2.1 COSMETIC PRODUCTS WITHOUT/WITH NATURAL PRESERVATIVES 17 2.2 PRESERVATIVES, ANTIMICROBIAL, ANTISEPTIC, ANTIBACTERIAL 17 2.3 PRESERVATIVE-FREE VERSUS SELF-PRESERVING 18 3 SELF-PRESERVING COSMETICS 19 3.1 GOOD MANUFACTURING PRACTICE (GMP) 19 3.2 APPROPRIATE PACKAGING 20 3.3 WATER ACTIVITY 20 3.4 PH CONTROL 21 3.5 PRESERVATION OF PRODUCTS WITH ANTIMICROBIAL INGREDIENTS 21 3.5.1 Chelating agents 21 3.5.2 Surfactants 21 3.5.3 Antioxidants 22 3.5.4 Essential oils 22 4 LEGISLATION 23 4.1 THE COSMETICS STATUTORY ORDER 23 4.1.1 Labelling of cosmetic products 23 4.1.2 Declaration of contents 24 4.1.3 Durability date/shelf life 24 4.1.4 Safety 25 5 SURVEY 27 5.1 SURVEY OF NON-PRESERVED/NATURAL-PRESERVED COSMETIC PRODUCTS 27 5.1.1 Purchase of cosmetic products in retail shops 28 5.1.2 Purchase of cosmetic products via the Internet 28 5.1.3 Types of products in the survey 29 5.2 DATABASE OF THE INVESTIGATED COSMETIC PRODUCTS 30 3
Page 1: Survey and health assessment of cos
Page 5: 8.3.4 Allergy 71 8.3.5 Critical imp
Page 9 and 10: Summary and conclusions Background
Page 11 and 12: More than 60 of the 459 substances
Page 13: � 15 of the “non-preserved” p
Page 16 and 17: 16 In the winter 2008/2009, the Dan
Page 18 and 19: 18 Ingredients defined as preservat
Page 20 and 21: 20 In short, the Good Manufacturing
Page 22 and 23: 22 � Cationic surfactants (such a
Page 24 and 25: 24 � Declaration of contents, i.e
Page 27 and 28: 5 Survey One of the purposes of thi
Page 29 and 30: the products found via the Internet
Page 31 and 32: that there are mistakes on the labe
Page 33 and 34: cosmetic products in the different
Page 35 and 36: Table 5-5 Overview of the different
Page 37 and 38: INCIName CAS No Chemical name or de
Page 39 and 40: INCIName CAS No Chemical name or de
Page 41 and 42: product contains benzyl alcohol (pr
Page 43 and 44: Even though these ingredients are f
Page 45 and 46: INCI name extract Effect Source* No
Page 47 and 48: Marketed as Product type Shelf life
Page 49 and 50: INCI name Function Marketing descri
Page 51: This cross-examination of the infor
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54 Table 6-3 Measured content of th
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7 Antibacterial effects of the sele
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7.2 Antibacterial effects of the fo
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� Five of the analyzed products c
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64 effects by inhalation of the fou
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66 Another long-term study showed a
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68 Chemical name 3,7-Dimethylocta-1
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70 8.3 Limonene 8.3.1 Occurrence an
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72 Cross sensitization between gera
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74 8.4.4 Allergy SCCNFP has include
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76 validated and there was no confi
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78 sensitization occurs, it will pr
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80 antibacterial properties. The in
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82 Danish EPA, 2005. “Survey of l
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84 Griem et al., 2003. Griem, P., G
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86 (SEAC, Unilever). http://www.rif
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Appendix A: Extractions from the da
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92 Furthermore, the database contai
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94 � It is not the INCI name that
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96 Table 2.1 All 459 ingredients li
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98 Table 2.1 All 459 ingredients li
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100 Table 2.1 All 459 ingredients l
Page 102 and 103:
Page 104 and 105:
Page 106 and 107:
Page 108 and 109:
Page 110 and 111:
Page 112 and 113:
Page 114 and 115:
114 INCIName CAS No Table 2.1 All 4
Page 116 and 117:
116 INCIName CAS No PERSEA GRATISSI
Page 118 and 119:
118 INCIName CAS No PARAFFIN 8002-7
Page 120 and 121:
120 INCIName CAS No DISTEAROYLETHYL
Page 122 and 123:
Table 2.2 All 459 ingredients liste
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Page 126 and 127:
Page 128 and 129:
Page 130 and 131:
Page 132 and 133:
Page 134 and 135:
INCIName CAS No LANOLIN LAURYL ALCO
Page 136 and 137:
INCIName CAS No MESEMBRYANTHEMUM CR
Page 138 and 139:
INCIName CAS No PERSEA GRATISSIMA O
Page 140 and 141:
INCIName CAS No ROSA DAMASCENA FLOW
Page 142 and 143:
INCIName CAS No SODIUM BEESWAX Tabl
Page 144 and 145:
INCIName CAS No THEOBROMA CACAO BUT
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146
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Tabel 3.1 All 244 ingredients in co
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Page 152 and 153:
Page 154 and 155:
Page 156 and 157:
Page 158 and 159:
Page 160 and 161:
Page 162 and 163:
162 Tabel 3.2 All 327 diferent ingr
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Page 166 and 167:
Page 168 and 169:
Page 170 and 171:
Page 172 and 173:
Page 174 and 175:
Page 176 and 177:
Page 178 and 179:
Page 180:
180 INCI Name CAS No RUMEX ACETOSEL
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