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Descargar PDF - Hospital San José Tec de Monterrey

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Radiocirugía en neurinomas <strong>de</strong>l acústicoReporte preliminar <strong>de</strong>l primer caso tratado en el <strong>Hospital</strong> <strong>San</strong> JoséNo. 27 • Volumen 9líquido cefalorraquí<strong>de</strong>o (5 casos, 14 %), infección <strong>de</strong>herida quirúrgica (1 caso), trombosis venosa profunda(1 caso) y necesidad <strong>de</strong> tarsorrafia (6 casos, 17 %).El control tumoral fue prácticamente igual en ambosgrupos.ConclusiónEl manejo óptimo <strong>de</strong> los neurinomas <strong>de</strong>l acústicoes un tema controversial y que aún se encuentra en<strong>de</strong>bate. Se ha encontrado que la radiocirugía comoterapia primaria o adyuvante es una opción efectiva,<strong>de</strong> baja morbilidad y <strong>de</strong> muy buen pronóstico comparadacon la microcirugía.Sin embargo, es importante recordar que no todos lospacientes son candidatos a esta modalidad <strong>de</strong> tratamiento,e igualmente existen barreras socioeconómicasy <strong>de</strong> recursos hospitalarios. Los pacientes <strong>de</strong> edadavanzada con tumores pequeños pue<strong>de</strong>n ser candidatosa observación, y pacientes con tumores mayores a35 mm <strong>de</strong>ben ser sometidos a resección microquirúrgica,aunque cada caso <strong>de</strong>be ser evaluado en formaindividual.Referencias bibliográficas1. Frosch MP, Anthony DC, De Girolami U. Peripheral nervesheath tumors. En: Robbins & Cotran Pathologic Basis of Disease.Kumar V, Abbas A, Fausto N. Elsevier Inc. 7a. Edición Phila<strong>de</strong>lphia,2005, pp 1411.2. Yamakami I, Uchino Y, Kobayashi E, Yamaura A. Conservativemanagement, gamma-knife radiosurgery, and microsurgeryfor acoustic neurinomas: a systematic review of outcome and riskof three therapeutic options. Neurol Res 2003;25:682-690.3. Propp JM, McCarthy BJ, David FG, Preston-Martin S. Descriptiveepi<strong>de</strong>miology of vestibular schwannomas. Neuro Oncol2006;8:1-11.4. Matthies C, Samii M. Management of 1000 vestibular schwannomas(acoustic neuromas): clinical presentation. Neurosurgery1997;40:1-9.5. Hasegawa T, et al. Stereotactic radiosurgery for vestibularschwannomas: analysis of 317 patients followed more than 5years. Neurosurgery 2005;57:257-264.6. Iwai Y, Yamanaka K, Shiotani M, Uyama T: Radiosurgery foracoustic neuromas: results of low-dose treatment. Neurosurgery2003;53:282-287.7. Andrews DW, Suarez O, Goldman HW, Downes MB, BednarzG, Corn BW, Werner-Wasik M, Rosenstock J, Curran WJJr: Stereotactic radiosurgery and fractionated stereotactic radiotherapyfor the treatment of acoustic schwanomas: comparativeobservations of 125 patients treated at one institution. Int J RadiatOncol Biol Phys 50:1265–1278, 2001.8. Myrseth E, Pe<strong>de</strong>rsen PH, Moller P, Lund-Johansen M. Treatmentof vestibular schwannomas. Why, when and how? ActaNeurochir 2007;149:647-660.9. Kondziolka D, Lunsford LD, McLaughlin MR, Flickinger JC.Long-term outcomes after radiosurgery for acoustic neuromas. NEngl J Med 1998;339:1426-1433.10. Flickinger JC, Kondziolka D, Niranjan A, Lunsford L. Resultsof acoustic neuroma radiosurgery:an analysis of 5 years’ experienceusing current methods. J Neurosurg 2001;94:1-6.11. Flickinger JC, Kondziolka D, Pollock BE, Lunsford LD. Evolutionin technique for vestibular schwannoma radiosurgery and effecton outcome. Int J Radiat Oncol Biol Phys 1996;36:275-280.12. Subach BR, Kondziolka D, Lunsford LD, Bissonette DJ, FlickingerJC, Maitz AH. Stereotactic radiosurgery in the managementof acoustic neuromas associated with neurofibromatosis-type 2. JNeurosurg 1999;90:815-822.13. Samii M, Matthies C. Management of 1000 vestibular schwannomas(acoustic neuromas): surgical management and resultswith an emphasis on complications and how to avoid them. Neurosurgery1997;40(1):11-23.14. Foote KD, Friedman WA, Buatti JM, et al. Analysis of risk factorsassociated with radiosurgery for vestibular schwannoma. JNeurosurg 2001;95:440-449.15. Spiegelmann R, Lidar Z, Gofman J, et al. Linear acceleratorradiosurgery for vestibular schwannoma. J Neurosurg 2001;94:7-13.16. Martens F, Verbeke L, Piessens M, et al. Stereotactic radiosurgeryof vestibular schwannomas with a linear accelerator. ActaNeurochir Suppl 1994;62:88-92.17. Pollock BE, et al. Patient outcomes after vestibular schwannomamanagement: A prospective comparison of microsurgical resectionand stereotactic radiosurgery. Neurosurgery 2006;59:77-85.Correspon<strong>de</strong>ncia:Dr. Enrique Caro OsorioEmail: ecaro@itesm.mxCiencias Clínicas 17

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