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N° 3 - Salute per tutti

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Pierfrancesco Morganti 1<br />

Lee Yuanhong 2<br />

G. Morganti 3<br />

1 Professor of Applied Cosmetic Dermatology,<br />

II Università di Napoli<br />

Head of R&D, Mavi Sud s.r.l., Aprilia (LT)<br />

Visiting Professor of China Medical<br />

University Shenyang<br />

Secretary general of I.S.C.D.<br />

2 No.1 Hospital of China Medical<br />

University Shenyang (PRC)<br />

3 Technical Director Mavi Sud s.r.l., Aprilia (LT)<br />

Nanostructured products:<br />

technology and future<br />

hat is<br />

W nanotechnology<br />

SU M M A R Y<br />

Nanotechnology is understood<br />

as the characterization,<br />

type, production and use<br />

of structures and systems the<br />

exact size and shape of which<br />

must be measured on a nanometric<br />

scale. 1<br />

Nanotechnologies are the set of<br />

methods and techniques for<br />

processing matter on an atomic<br />

and molecular scale to create<br />

p roducts presenting special<br />

and improved chemical-physical<br />

features as compared to<br />

conventional ones.<br />

What size is a nanometer (nm)?<br />

A nanometer corresponds to one billionth of a<br />

meter (Figure 1).<br />

Considering that a bacterium measures 1000<br />

nm and that the distance between two carbon<br />

atoms of an organic molecule is 0.15 nm, one<br />

can easily comprehend how difficult it must be<br />

Figure 1. The nanometric scale.<br />

Nanostructured products:<br />

technology and future<br />

Nanotechnologies are the set of methods and techniques for processing matter on an<br />

atomic and molecular scale to create products presenting special and improved chemical-physical<br />

features as compared to conventional ones. With the current technological<br />

k n o w - h o w, it is already possible to build diff e rent types of nanostructures (DNA, proteins,<br />

cells or viruses, etc.) on special chips that can help to better understand the function<br />

<strong>per</strong>formed by proteins in cells. Thanks to nanotechnology, it is now possible to modify<br />

the chemistry and the topography of the substratum of cell cultures so as to enable<br />

them to mime the extracellular matrix, in such a way that the same signals used by cells<br />

in vivo are released. With the use of other technological platforms, it is possible to obtain<br />

thin nanostructured films organized as nets, capable of providing a huge surface that is<br />

available for interaction with the skin tissue and the external environment. An example<br />

of this is the production of 240 nm chitin nanofibrils capable of accelerating in a physiological<br />

manner the reparation of damaged skin. Chitin nanofibrils can also be used as<br />

c a rriers for pharmacological or cosmetic use.<br />

KE Y W O R D S: Nanotechnologies, Chitin nanofibrils<br />

for the industry to work with such scales!<br />

Nevertheless, it is common knowledge that<br />

n a n o m a t e r i a l s p resent mechanical, optical,<br />

chemical, magnetic or electric pro<strong>per</strong>ties that<br />

are completely different from the raw material<br />

from which they are generated. 2<br />

Journal of Plastic Dermatology 2008; 4, 3 253

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