14.03.2015 Views

ITALIAN JOURNAL OF PUBLIC HEALTH Aspetti economici ... - Ijph.it

ITALIAN JOURNAL OF PUBLIC HEALTH Aspetti economici ... - Ijph.it

ITALIAN JOURNAL OF PUBLIC HEALTH Aspetti economici ... - Ijph.it

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

IJPH - Year 8, Volume 7, Number 3, Suppl. 2, 2010<br />

I T A L I A N J O U R N A L O F P U B L I C H E A L T H<br />

minor numero di viaggi) [22].<br />

Alla luce della considerazioni sopra esplic<strong>it</strong>ate,<br />

appare opportuno estendere l’impiego del<br />

nuovo regime all’interno del terr<strong>it</strong>orio nazionale<br />

in quanto esso, oltre a presentare risultati clinici<br />

di prim’ordine, comporta notevoli vantaggi<br />

<strong>economici</strong> associati prevalentemente alla<br />

possibil<strong>it</strong>à di gestione domiciliare della nuova<br />

terapia da parte dei pazienti.<br />

Bibliografia<br />

1) Giuliani G, Lucioni C, Mazzi S, De Carli C, Jamieson C.<br />

Valutazione di convenienza economica comparata tra un<br />

farmaco orale (capec<strong>it</strong>abina) e una terapia parenterale a base di<br />

5-FU (regime Mayo) nel trattamento del tumore del colon-retto<br />

metastatizzato. Pharmacoeconomics, Italian Research Articles<br />

2002;4 (1):13-38.<br />

2) La Torre G, Chiaradia G, de Waure C, Nicolotti N, Monteduro<br />

A, Ricciardi W. Report HTA del vaccino quadrivalente anti-HPV<br />

Gardasil. Ital J Public Health 2009;6(suppl 2).<br />

3) Belovich D, Hux M, Douglas P, Maroun JA, Sommer<br />

N. Cost-effectiveness of capec<strong>it</strong>abine in combination w<strong>it</strong>h<br />

oxaliplatin (XELOX) compared w<strong>it</strong>h FOLFOX for the treatment<br />

of metastatic colorectal cancer: A Canadian evaluation. J Clin<br />

Oncol 2009;27 (suppl; abstract e17502).<br />

4) Garrison L, Guiliani G, Ducournau P, et al. Cost analysis of<br />

XELOX vs. FOLFOX-4 ± Avastin (bev) in metastatic colorectal<br />

cancer (MCRC) from an Italian hosp<strong>it</strong>al perspective. ISPOR<br />

Europe 2007b, 20–23 October, Dublin, Ireland, Abstr PCN38.<br />

5) Garrison L, Cassidy J, Saleh M, et al. Cost comparison<br />

of XELOX compared to FOLFOX4 w<strong>it</strong>h or w<strong>it</strong>hout Avastin<br />

(bev) in metastatic colorectal cancer. J Clin Oncol 2007a<br />

ASCO Annual Meeting Proceedings Part I; 25(18S) June 20<br />

Suppl:4074.<br />

6) Perrocheau G, Bennouna J, Ducreaux M, et al. Costminimization<br />

analysis of a phase III study of capec<strong>it</strong>abine<br />

+ oxaliplatin (XELOX) vs infusional 5-FU/LV + oxaliplatino<br />

(FOLFOX-6) as first-line treatment for metastatic colorectal<br />

cancer (MCRC) in the French setting. J Clin Oncol 2007<br />

ASCO Annual Meeting Proceedings Part I; 25(18S) June 20<br />

Suppl:4083.<br />

7) Jansman FGA, Postma MJ, van Hartskamp D, Willemse PHB,<br />

Brouwers JRBJ. Cost-benef<strong>it</strong> analysis of capec<strong>it</strong>abine versus<br />

5-fluorouracil/leucovorin in the treatment of colorectal cancer<br />

in the Netherlands. ClinTher 2004;26(4):579-89.<br />

8) Cassidy J, Douillard J-Y, Twelves C, et al. Pharmacoeconomic<br />

analysis of adjuvant capec<strong>it</strong>abine vs intravenous 5 FU/LV in<br />

Dukes’ C colon cancer: X-ACT trial. BJC 2006;94:1122-29.<br />

9) Conroy T, Hebbar M, Bennouna J, et al. Qual<strong>it</strong>y-of-life<br />

findings from a randomised phase-III study of XELOX vs<br />

FOLFOX-6 in metastatic colorectal cancer. BJC 2010;102:59-67.<br />

10) Manidakis N, Fragoulakis V, Pectasides D, Fountzilas G.<br />

XELOX vs FOLFOX 6 as an adjuvant treatment in colorectal<br />

cancer: an economic analysis. Curr Med Res and Op<br />

2009;25(3):797-805.<br />

11) Brandi G, Di Cicilia R, Di Battista M, et al. Capec<strong>it</strong>abine<br />

(CAP) based regimens vs infusional 5-FU/FA in metastatic<br />

colorectal cancer cost/effectiveness: the differences across<br />

the atlantic Ocean. Ann Oncol 2008; 19 (suppl 9). Disponibile<br />

online al s<strong>it</strong>o: http://annonc.oxfordjournals.org/content/19/<br />

suppl_9/ix63.full.pdf+html (Ultimo accesso: 15.06.2010).<br />

12) Antonuzzo L, Negrini C, Gasperoni S, et al.<br />

Pharmacoeconomic analysis of adjuvant chemotherapy w<strong>it</strong>h<br />

fluoropymidine in colon cancer. Ann Oncol 2008; 19 (suppl<br />

9). Disponibile online al s<strong>it</strong>o: http://annonc.oxfordjournals.<br />

org/content/19/suppl_9/ix63.full.pdf+html (Ultimo accesso:<br />

15.06.2010).<br />

13) Chu E, Cartwright T H. Pharmacoeconomic benef<strong>it</strong>s of<br />

capec<strong>it</strong>abine-based chemotherapy in metastatic colorectal<br />

cancer. J Clin Oncol 2008; 26(13): 2224-6.<br />

14) Shiroiwa T, Furkuda T, Tzutani K. Health util<strong>it</strong>y scores of<br />

colorectal cancer based on societal preference in Japan. Qual<br />

Life Res 2009;18:1095–103.<br />

15) Lopatriello S, Amoroso D, Donati S, et al The CAP-CR<br />

study: direct medical costs in Italian metastatic colorectal<br />

cancer patients on first line infusional 5-Fluorouracil or oral<br />

capec<strong>it</strong>abine. EJC 2008, 44: 2615-22.<br />

16) Araújo DV, Cirrincione A. Cost of colorectal cancer<br />

treatment in elderly patients. BJGG 2006;9(1): 72-81.<br />

17) Lopatriello S, Negrini C, Amoroso D, Donati S. Gestione<br />

del paziente affetto da tumore del colon-retto metastatico:<br />

conseguenze economiche dei diversi percorsi terapeutici.<br />

Farmacoeconomia e percorsi terapeutici 2009;10(3): 141-6.<br />

18) Shiroiwa T, Furkuda T, Tzutani K. Cost-effectiveness<br />

analysis of XELOX for metastatic colorectal cancer based on<br />

the NO 16996 and NO 16967 trials. BJC 2009;101:12-8.<br />

19) Shiroiwa T, Fukuda T, Tsutani K. Cost-effectiveness<br />

analysis of bevacizumab combined w<strong>it</strong>h chemotherapy for<br />

the treatment of metastatic colorectal cancer in Japan. Clin<br />

Ther 2007;29(10): 2256-67.<br />

20) Saltz L B, Clarke S, Diaz-Rubio E, et al. Bevacizumab in<br />

combination w<strong>it</strong>h oxaliplatin-based chemotherapy as first-line<br />

therapy in metastatic colorectal cancer: a ranzomized phase III<br />

study. J Clin Oncol 2008;26: 2013-19.<br />

21) Rothenberg M L, Cox J V, Butts C, et al. Capec<strong>it</strong>abine<br />

plus oxaliplatin (XELOX) vs 5-fluorouracil/folinic acid plus<br />

oxaliplatin (FOLFOX-4) as second line therapy in metastatic<br />

colorectal cancer: a randomized phase III noninferior<strong>it</strong>y study.<br />

Ann Oncol 2008;19:1720-6.<br />

22) Di Costanzo F, Antonuzzo L, Rotella V, Negrini C. Analisi<br />

farmacoeconomica in pazienti trattati con capec<strong>it</strong>abina in<br />

terapia adiuvante. Clin Prac 2008; 10:17-25.<br />

23) Goerner M, Riemer-Hommel P. Economic impact of<br />

Alternative Adjuvant Chemoterapy Regimens for Stage III<br />

Colon Cancer. Onkologie 2009; 32:647-52.<br />

C A P I T O L O 5 S 6 9

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!