Products at a Glance 2024

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www.pelobiotech.com • May require additional optimization for specific cell types. • Availability may be limited compared to FBS. • Animal Origin-Free Media Animal origin-free (AOF) media, on the other hand, prioritizes the exclusion of any components sourced directly from animals, such as serum, addressing ethical concerns, regulatory constraints, and contamination risks. While AOF media eliminates the use of animal-derived products, it may still contain complex, chemically defined components. This broader category provides an alternative for researchers seeking to create a culture environment free of animal-origin components while allowing for flexibility in the specific formulation. Advantages: • Completely devoid of any animal-derived components, addressing ethical concerns and regulatory considerations. • Reduced risk of introducing contaminants from animal sources, ensuring a cleaner and more controlled culture environment. • Suitable for applications where the presence of animal-derived components is restricted, such as in the production of therapeutic proteins for human use. Disadvantages: • Can be more expensive compared to media containing animal-derived components. • May require additional optimization for specific cell types, as the absence of certain factors present in animalderived products may impact cell growth or function. • Availability of well-defined formulations for all cell types may be limited. Defined Media Defined media represent a meticulous approach to cell culture formulation, offering researchers precise control over every component's composition. By excluding undefined or complex components, defined media eliminate batch variability, ensuring reproducibility in experimental outcomes. This level of specificity is particularly advantageous for detailed research where a clear understanding and manipulation of the nutritional and signaling factors influencing cell behavior are crucial. Defined media are ideal for experiments requiring consistency, allowing researchers to tailor the culture environment with exacting precision. Advantages: • Offers precise control over the composition of the media, allowing for reproducibility and consistency between batches. • Eliminates batch-to-batch variability associated with complex, undefined components, promoting reliability in experimental outcomes. • Ideal for research where a clear understanding and manipulation of individual components are crucial. Disadvantages: • More expensive compared to media containing complex, undefined components. • Optimization may be required for specific cell types, as the absence of certain factors present in undefined media might affect cell behavior. • The formulation process can be complex, requiring careful consideration of the nutritional needs of the cells. 28

www.pelobiotech.com Defined media from our portfolio: Cat# Product Quantity Application PB-YSP002 CellCor TM CD MSC 500 ml Human MSC Expansion, GMP PB-YSP017 CellCor TM EXO CD 500 ml Human MSC expansion & Exosome production PB-YSP018 CellCor TM Keratinocytes CD AOF 500 ml Culture of human keratinocytes PB-YSP019 CellCor TM MSC CD AOF 500 ml MSC Expansion, animal origin free; RUO & GMP PB-YSP007 CellCor TM DPC CD 500 ml Culture of human dermal papilla cells PB-C-MH-350-3111 PB-C-MH-360-8699 PB-C-MH-895-0099-d PB-C-MH-100-2199-d PB-C-MH-100-4099-d PB-C-MH-300-1099 PB-C-MH-341-7499 PB-C-MH-350-0099 PB-C-MH-352-0096 PB-C-MH-400-9099-d PB-C-MH-442-3699-M Cellovations Bronchial Epithelial Cell Growth Medium Kit, defined Cellovations Corneal Epithelial Cell Growth Medium Kit enhanced, defined Cellovations Co-Culture Growth Medium AE Kit Cellovations Endothelial Cell Growth Medium Kit enhanced, defined Cellovations Microvascular Endothelial Cell Growth Medium Kit enhanced, defined Keratinocyte Growth Medium Kit enhanced, defined Oral Epithelial Cell Growth Medium Kit, defined Airway Epithelial Cell Growth Medium Kit, defined Renal Epithelial Cell Growth Medium Kit, defined Fibroblast Growth Medium Kit defined Adipocyte Maintenance Medium Kit enhanced, defined 500 ml Culture of human bronchial epithelial cells 500 ml Culture of human corneal epithelial cells 500 ml Co-culture of Human adipocytes and endothelial cells 500 ml Culture of human endothelial cells from large vessels under FBSfree and defined conditions 500 ml Culture of human endothelial cells from small vessels under FBSfree and defined conditions 500 ml Culture of human keratinocytes 500 ml Culture of human oral epithelial cells 500 ml Culture of human airway epithelial cells 500 ml Culture of human renal epithelial cells 500 ml Culture of human fibroblast 500 ml Maintenance of human adipocytes 29