PET-CENTRETS ÅRSRAPPORT 2008 - Aarhus Universitetshospital

Sukker stofskifte og
sukker transport
Sporstof
[ 18 F]fluorodeoxyglucose, [ 11 C]glucose, [ 18 F]-fluorogalactose,
3-O-[ 11 C]methylglucose
Gennemblødning [ 15 O]water, [ 13 N]ammonia, [ 15 O]butanol
Ilt stofskifte [ 15 O]oxygen, [ 11 C]acetate
Blod volumen [ 15 O]carbon monoxide, [ 11 C]carbon monoxide
Amino syre [ 18 F]6-fluoroDOPA, [ 11 C]methionine, [ 11 C]-methyl-alpha-isobutyric
acid (MeAIB),a-[18F]fluoro-b-alanine
[ 11 C]asparagine, [ 11 C]2,4-diaminobutyric acid, [ 11 C]aspartic
acid
Transportør ligander DAT: [ 11 C] b-CIT-FE, [ 11 C]NS 2214
SERT: [ 11 C]DASB, [ 11 C]NS9531, [ 11 C]NS9762, [11C]NS
6417, [ 11 C]NS 2495, [ 11 C]NS 4194, [ 11 C]NS 2456, [ 11 C]NS
2381, [ 11 C]venlafaxine, [ 11 C]nefopam, [ 11 C]nitroquipazine
NET: [ 11 C]-SS-MeNER
Receptor ligander [ 11 C]Raclopride (D2,3 antagonist), [ 11 C]-WAY 100,635 (5-
HT1A antagonist), [ 11 C]PK 11195 (peripheral benzodiazepine
receptor ligand), [ 11 C]mirtazapine (adrenoceptors),
[ 11 C]MDL100,907 (5-HT2A antagonist, [ 11 C]Yohimbine
(adrenoceptors), [ 11 C]FLB 457 (D2 antagonist), [ 11 C]mianserin
(adrenoceptors), [ 11 C]NMSP (5-HT and D2 antagonist),
[ 11 C]SCH23390 (D1 antagonist), [ 11 C]NNC112 (D1 antagonist),
[ 11 C]SKF 75670 (D1 agonist), [ 11 C]SKF 82957 (D1
agonist), [ 11 C]NPA (D2 agonist), [ 11 C]CP 643,051 (NK1 antagonist),
[ 11 C]GR 205171 (NK1 antagonist), [ 11 C]SB 207145 (5-
HT4 antagonist), [ 11 C]melatonin (MT receptor ligand), [ 11 C]NS
3957(nicotinergic system), [ 11 C]methylamantadine (NMDA
antagonist), [ 11 C]Flumazenil (dibenzodiazepine receptor
ligand).
Hypoxi markør [ 18 F]fluoromisonidazole, [ 18 F]-FAZA
Forskellige [ 18 F]fluoride (bone metabolism), [ 11 C]harmine (MAO inhibitor),
[ 11 C]rolipram (PDE IV inhibitor), [ 11 C]PIB (bamyloid
plaque labeling), [ 11 C Tarceva (EPG-ligand),
[ 11 C]methamphetamine and [ 11 C] b,b-difluoromethamphetamine,
[ 11 C]Ral1 (PDEV ligand).
Tabel: Sporstoffer til rådighed ved Århus Sygehusets PET centret (sporstoffer godkendt
til human brug i kursiv).
Forskningsaktiviteter
Ved siden af varetagelse af rutineopgaver deltog PET-centrets kemikere også i 2008 meget
aktiv i PET-centrets forskningsaktiviteter, både iht. egne mere radiokemisk relaterede
PET-centret i Århus | Årsrapport 2008