PET-CENTRETS ÅRSRAPPORT 2008 - Aarhus Universitetshospital

0
Concentration of radioactivity (kBq/mL blood)
Concentration of of radioactivity radioactivity (kBq/mL (kBq/mL blood)
blood)
Concentration of radioactivity (kBq/mL blood)
250
200
150
100
50
0
0 1 2 3 4 80 90
300
250
200
150
100
50
Time after injection of FDGal (minutes)
PET-centret i Århus | Årsrapport 2008
Exp. 4: approx. firstorder firstorder kinetics
∆ Arterial input
○ Portal input
− c dual
Concentration of of radioactivity (kBq/mL tissue)
Concentration of of radioactivity radioactivity (kBq/mL (kBq/mL tissue)
tissue)
160
140
120
100
80
60
40
20
Exp. 6: intermediate kinetics
∆ Arterial input
○ Portal input
− c dual
0
0 1 2 3 4 80 90
250
200
150
100
50
Time after injection of FDGal (minutes)
0
0 1 2 3 4 80 90
Time after injection of FDGal (minutes)
Concentration of radioactivity (kBq/mL tissue)
0
0 15 30 45 60 75 90
60
50
40
30
20
10
Exp. 10: nearsaturated nearsaturated kinetics
∆ Arterial input
○ Portal input
− c cdual dual
Time after injection of FDGal (minutes)
Time after injection of FDGal (minutes)
▲PET data
▲PET data
0
0 15 30 45 60 75 90
50
40
30
20
10
0
0 15 30 45 60 75 90
Time after injection of FDGal (minutes)
▲PET data
Figur 4: Griseforsøg med iv injektion af FDGal. Venstre: Tidsforløb af radioaktivitetskoncentrationer
i leverens blodkar (som anført på figuren). Højre: Tidsforløb af radioaktivitetskoncentrationer
i leveren. Galaktose blev givet som konstant infusion: Øverst:
blodkoncentration af galaktose < 0,01 mM. Midt: 0,62 mM. Nederst: 6,65 mM.