Videnskabelig årsrapport 2005 - Rigshospitalet

Abdominalcentret
Abdominalcentret
Anæstesi- og
Operationsklinik
Videnskabeligt personale
Seniorforskere
Professor, overlæge, dr.med. Niels H.
Secher
Reservelæge Henning Bay Nielsen
Ph.d.-studerende
Chie Yoshiga, Japan
Peter Rasmsussen
Udenlandske gæsteforskere
Ph.D. Ellen Dawson, England
Ph.D. James Fisher, Birmingham, UK
Ph.D. Craig Grandall, Texas
Ph.D. student, Emma Hart, London, UK
M.D., Ph.D. Johannes van Lieshout,
Holland
Ph.D. Shigehiko Ogoh, Texas
Professor, Ph.D. Peter Raven, Texas
Ph.D. Manabu Shibasaki, Texas
Ph.D. Stefanos Volianitis, England
Andre forskere
Stud.med. Øivind Jans
Stud.scient. Stefan Mortensen
Stud.med. Christian Selmer
Cand.scient. Morten Zaar
Vigtigste satsningsområder
inden for forskningen
Human kredsløbsfysiologi.
Monitorering af det centrale
blodvolumen.
Perioperativ patofysiologi.
Publikationer
Disputatser og ph.d.-afhandlinger
forsvaret i året
Dalsgaard M. Fuelling cerebral activity in
exercising man (disputats).
København: Eget forlag; 2005:1-63.
Forsvaret den 2/12 2005 ved
Københavns Universitet, Det
Sundhedsvidenskabelige Fakultet.
Westerhof BE. Blood pressure analysis on
time scales from seconds to days
(disputats). Amsterdam: Eget forlag;
2005:1-192. Forsvaret den 13/12
2005 ved Amsterdam Universitet.
Videnskabelige artikler
A. Førsteforfatter fra
forskningsenheden
Bay NH, Thomsen C, Chen X, Andersen
CB, Toft BG, Søndergaard L, et al.
Arhytmogenic right ventricular
cardiomyopathy: a presentation of
thirty consecutive patients. Heart
Drug 2005;5:146-52.
Bay NH, Secher NH, Clemmesen O, Ott
P. Maintained cerebral and skeletal
muscle oxygenation during maximal
exercise in patients with liver
cirrhosis. J Hepatol 2005;43(2):266-
71.
Krantz T, Warberg J, Secher NH. Venous
oxygen saturation during
normovolaemic haemodilution in the
pig. Acta Anaesthesiol Scand
2005;49(8):1149-56.
Nowak M, Holm S, Biering-Sorensen F,
Secher NH, Friberg L. "Central
command" and insular activation
during attempted foot lifting in
paraplegic humans. Hum Brain Mapp
2005;25(2):259-65.
Nybo L, Dalsgaard MK, Steensberg A,
Moller K, Secher NH. Cerebral
ammonia uptake and accumulation
during prolonged exercise in humans.
J Physiol 2005;563(Pt 1):285-90.
Ogoh S, Fisher JP, Dawson EA, White
MJ, Secher NH, Raven PB.
Autonomic nervous system influence
on arterial baroreflex control of heart
rate during exercise in humans. J
Physiol 2005;566(Pt 2):599-611.
Ogoh S, Dalsgaard MK, Yoshiga CC,
Dawson EA, Keller DM, Raven PB,
et al. Dynamic cerebral
autoregulation during exhaustive
exercise in humans. Am J Physiol
Heart Circ Physiol
2005;288(3):H1461-67.
Ogoh S, Fadel PJ, Zhang R, Selmer C,
Jans O, Secher NH, et al. Middle
cerebral artery flow velocity and
pulse pressure during dynamic
exercise in humans. Am J Physiol
Heart Circ Physiol
2005;288(4):H1526-31.
Secher NH, Quistorff B. Brain glucose
and lactate uptake during exhaustive
exercise. J Physiol 2005;568(Pt 1):3.
Secher NH, Van Lieshout JJ.
Normovolaemia defined by central
blood volume and venous oxygen
saturation. Clin Exp Pharmacol
Physiol 2005;32(11):901-10.
Shibasaki M, Secher NH, Johnson JM,
Crandall CG. Central command and
the cutaneous vascular response to
isometric exercise in heated humans.
J Physiol 2005;565(Pt 2):667-73.
Van Lieshout JJ, Harms MP, Pott F,
Jenstrup M, Secher NH. Stroke
volume of the heart and thoracic fluid
content during head-up and headdown
tilt in humans. Acta
Anaesthesiol Scand 2005;49(9):1287-
92.
B. Medforfatter fra forskningsenheden
Blomstrand E, Moller K, Secher NH,
Nybo L. Effect of carbohydrate
ingestion on brain exchange of amino
acids during sustained exercise in
human subjects. Acta Physiol Scand
2005;185(3):203-9.
Schou M, Dalsgaard MK, Clemmesen O,
Dawson EA, Yoshiga CC, Nielsen
HB, et al. Kidneys extract BNP and
NT-proBNP in healthy young men. J
Appl Physiol 2005;99(5):1676-80.
Videnskabelige priser
Niels H. Secher & Bjørn Quistorff.
Lundbeck Fonden, 2005.
Hepatologisk Klinik A
Videnskabeligt personale
Seniorforskere
Klinikchef, overlæge, dr.med. Bent Adel
Hansen
Professor, overlæge, dr.med. Helmer
Ring-Larsen
Overlæge, dr.med., ph.d. Fin Stolze
Larsen
Overlæge, dr.med. Mette Clausen
1. reservelæge, dr.med. Otto Clemmesen
1. reservelæge Frank Schiødt
Ph.d.-studerende
Klinisk assistent Flemming Tofteng
Klinisk assistent Hans R. Pedersen
Klinisk assistent Thomas Dethloff
Andre forskere
Bioanalytiker Bjørg Krog
Bioanalytiker Kirsten Prisholm
Bioanalytiker Liselotte Hansen
Bioanalytiker Mie Poulsen
Bioanalytiker Nine Scherling
Professor emeritus Niels Tygstrup
Reservelæge, Ph.D. Lars E. Schmidt
Reservelæge Martin Eefsenf
Studenterforskere
Stud.pharm. Philip Avnstrøm
Stud.pharm. Ghousia Javid
Stud.pharm. Martin Erbo Jensen
Stud.pharm. Sultan Ozturk
Vigtigste satsningsområder
inden for forskningen
Behandling af akut leversvigt.
Patofysiologi ved leversvigt og
hjerneødem.
Udvikling af levererstatningsbehandling.
Leverens genekspression af
akutfasereaktanter med henblik på
virkning af leverskade.
Endotoxinbetinget cholestase.
Behandling af kronisk hepatitis B og C.
Hæmodynamik ved kronisk leversygdom.
Behandling af alkoholisk hepatitis og
hepatorenalt syndrom.
Publikationer
Videnskabelige artikler
A. Førsteforfatter fra
forskningsenheden
Dethloff T, Knudsen GM, Hansen BA,
Larsen FS. Effects of porta-systemic
shunting and ammonia infusion on
cerebral flow autoregulation in the
rat. Neurocrit Care 2005;3(1):86-90.
Grønbæk K, Sonne J, Ring-Larsen H,
Poulsen HE, Friis H, Krarup HB.
Videnskabelig årsrapport 3