Videnskabelig årsrapport 2005 - Rigshospitalet

Diagnostisk Center
Janulaityte-Gunther D, Kucinskiene R,
Kupcinskas L, Pavilonis A,
Labanauskas L, Cizauskas S, Schmidt
U, Wadstrom T, Andersen LP. The
humoral immueresponse to
Helicobacter pylori infection in
children with gastrointestinal
symptoms. FEMS Immunol Med
Microbiol 2005;44(2):205-12.
Kong KF, Jayawardena SR, Indulkar SD,
del Puerto A, Koh CL, Høiiby N,
Mathee K. Pseudomonas aeruginosa
AmpR is a global transcriptional
factor that regulates expression of
AmpC and PoxB beta-lactamase,
proteases, quorum sensing, and other
virulence factors. Antimicrob Agents
Chemother 2005;49:4567-75.
Krogfelt KA, Andersen LP, Kusters JG.
Pathogenesis and host response in
Helicobacter infections. FEMS
Immunol Med Microbiol
2005;44(2):111.
Larsen M, Kromann H, Kharazmi A,
Nielsen SF. Conformationally
restricted anti-plasmodial chalcones.
Bioorganic & Med Chem Letters
2005;15:4858-61.
Malfroot A. Adam G, Ciofu O, Doring G,
Knoop C, Lang AB, Van Damme P,
Dab I, Bush A. Immunisation in the
current management of cystic fibrosis
patients. J Cyst Fribros 2005;4(2):77-
87.
Møller T, Borregaard N, Tvede M,
Adamsen L. Patient education – a
strategy for prevention of infections
caused by permanent central venous
catheters in patients with
haematological malignancies: a
randomized clinical trial. J Hosp
Infect 2005;61(4):330-41.
Nielsen MA, Grevstad B, A-Elgadir
TME, Kurtzhals JAL, Giha H,
Staalsoe T, Hviid L, Theander TG.
Differential induction of antibodies to
Plasmodium falciparum vaariant
surface antigens during the
transmission season in Darawesh
village Sudan. J Infect Dis
2005;192:520-7.
Ostrowski SR, Ullum H, Goka BQ,
Høyer-Hansen G, Adjei GO,
Pedersen BK, Akanmori BD,
Kurtzhals JAL. The plasma level of
the soluble urokinase receptor is
increased in malaria patients and
associated with a poor clinical or fatal
outcome. J Infect Dis 2005;191:1331-
41.
Permin H, Andersen LP: Inflammation,
immunity, and vaccines for
Helicobacter infection. Helicobacter
2005;(Suppl.1):21-5.
Permin H, Pedersen P, Høiby N. Det
sidste tilfælde af kopper i Danmark –
og de organisatoriske forhold i 1970.
Dansk Medicin Historisk Årbog
2005:115-144.
Quashie NB, Akanmori BD, Goka BQ,
Ofori-Adjei D, Kurtzhals JAL.
Pretreatment blood concentrations of
chloroquine in patients with malaria
infection: relation to response to
treatment. J Trop Ped 2005;51:149-
53.
Rasmussen TB, Skindersø ME, Bjarnsholt
T, Phipps RK, Christensen KB,
Jensen PØ, Andersen JB, Koch B,
Larsen TO, Hentzer M, Eberl L,
Høiby N, Givskov M. Identity and
effects of quorum sensing inhibitors
produced by Penicillium species.
Microbiol 2005;151:1325-40.
Rasti N, Falk KI, Donati D, Gyan BA,
Goka BQ, Troye-Blomberg M,
Akanmori BD, Kurtzhals JAL,
Dodoo D, Consolini R, Linde A,
Wahlgren M, Bejarano MT.
Circulating Epstein-Barr virus in
children living in malaria-endemic
areas. Scand J Immunol 2005;
61:461-5.
Rosenfeldt V, Vesikari T, Pang XL, Zeng
SQ, Tvede M, Paerregaard A. Viral
etiology and incidence of acute
gastroenteritis in young children
attending day-care centers. Pediatr
Infect Dis J 2005; 24(11):962-5.
Stensballe J, Looms D, Nielsen PN,
Tvede M. Hydrophilic-coated
catheters for intermittent
catherisation reduce urethral micro
trauma: a prospective, randomised,
participant-blinded, crossover study
of three different types of catheters.
Eur Urol 2005;48(6):978-83.
Wiese L, Nielsen X, Andresen K, Kjaer
A, David K. 16 S rDNA sequencing
revealed Citrobacter freundii as the
cause of liver abcess after banding of
rectal haemorrhoids. J Infect
2005;50(2):163-4.
Ytting H, Terslev L, Tvede M, Heslet L,
Høiby N: Antibiotic treatment in four
departments of a university hospital.
A descriptive period prevalence
study. Ugeskr Læger
2005;167(4):396-400.
C. Bidrag til multicenterforsøg og
lignende
Kerem E, Conway S, Elborn S, Heijerman
H and the Consensus Committee
(Høiby N). Standards of care for
patients with cystic fibrosis: a
European consensus. J Cyst Fibros
2005; 4:7-26.
Patologiafdelingen
Videnskabeligt personale
Seniorforskere
Laboratoriechef, dr.med. Niels Græm
Professor, dr.med. Elisabeth Ralfkiær
Professor, dr.med. Karsten Buschard
Overlæge, dr.med. Birgitte Ravn Juhl
Overlæge, dr.med. Claus B. Andersen
Overlæge, dr.med. Fritz Rank
Overlæge, dr.med. Grete Krag Jacobsen
Overlæge, dr.med. Henning Laursen
Overlæge, dr.med. Marianne Hamilton
Overlæge, dr.med. Maxwell Sehested
Overlæge, dr.med. Ole Frøkjær Thomsen
Overlæge, ph.d. Bodil Laub Petersen
Overlæge, ph.d. Lotte Nedergaard
Overlæge Helle Broholm
Overlæge Helle Jensen
Overlæge Nina Hastrup
Overlæge Søren Daugaard
Ph.d.-studerende
Cand.scient. Lena Ibsen
Cand.scient. Marielle Dejligbjerg
Cand.scient. Mette Damgaard Nielsen
Cand.scient. Tina Friis
Cand.med. Marie-Louise Hartoft-Nielsen
Cand.med. Tina Klitmøller Sørensen
Klinisk assistent Christian Bjørn Poulsen
Klinisk assistent Christopher Burton
Klinisk assistent Lene Dissing Sjø
Klinisk assistent Lise Mette Gjerdum
Udenlandske gæsteforskere
David Funda, ph.d. læge, Tjekkiet
Petra Funda, læge, Tjekkiet
Øvrigt forskningspersonale
Afdelingslæge, dr.med. Lise Christensen
Afdelingslæge, dr.med. Vera
Timmermans
Afdelingslæge, ph.d. Ben Vainer
Afdelingslæge Anne Mellon Mogensen
Afdelingslæge Lisa Leth Maroun
Afdelingslæge Lise Grupe Larsen
1. reservelæge, ph.d. Eric Santoni-Rugiu
1. reservelæge Birgitte Grønkjær-Toft
1. reservelæge Mahin Mohammadi
Reservelæge Dorrit Krustrup
Reservelæge Jane Preuss Hasselby
Reservelæge Marianne Gürtler Cortez
Reservelæge Micha Bank
Læge, ph.d. Knud Josefsen
Cand.polyt., ph.d. Thomas Østerbye
Cand.scient., ph.d. Allan Røske-Nielsen
Cand.scient., ph.d. Lars Høllund Jensen
Cand.scient., ph.d. Morten Grauslund
Cand.scient., ph.d. Morten Schou
Cand.scient. David Guterbaum
Cand.scient. Henrik Dyrbye
Cand.scient. Åsa Åkasson
Cand.scient.hum., ph.d. Ann-Louise
Bergstrøm
Stud.scient. Uffe Olesen
Stud. med., skolarstipendiat Torsten Holm
Nielsen
Vigtigste satsningsområder
inden for forskningen
Klinisk onkologisk patologi.
Eksperimetel patologi og molekylær
cancerterapi.
Transplantationspatologi/immunologi,
herunder diabetes.
Neurodegenerative sygdomme.
Reproduktion/føtalpatologi.
Publikationer
Disputatser og ph.d.-afdhandlinger
forsvaret i året
Agander TKS. Elucidation of the
molecular interaction of
bisdioxopiperazine anti-cancer agents
with their cellular target DNA
topoisomerase II-alpha by mutational
analysis. (ph.d.-afhandling).
København: Eget forlag; 2005:3-91.
Forsvaret den 24/11 2005 ved
Københavns Universitet, Det
Sundhedsvidenskabelige Fakultet.
Bergstrøm AL. Neuropathological
mechanisms of the prion diseases
(ph.d.-afhandling). København: Eget
forlag; 2005:1-92. Forsvaret den
12/12 2005 ved Københavns
Videnskabelig årsrapport 17