Videnskabelig årsrapport 2005 - Rigshospitalet

Neurocentret
Montrouge: John Libbey Eurotext;
2005:367-88.
Thygesen KS, Wolf P.
Valproatencefalopati. Ugeskr Laeger
2005;167:3793-4.
H:S
Hukommelsesklinikken
Videnskabeligt personale
Seniorforskere
Cand.jur., ph.d. Dorthe Vennemose Buss
Overlæge, dr.med. Steen Hasselbalch
Afdelingslæge, ph.d. Peter Johannsen
Overlæge, ph.d. Jørgen Erik Nielsen
Professor, overlæge, dr.med. Gunhild
Waldemar
Cand.med., ph.d. Frans Waldorff
Ph.d.-studerende
Cand.polyt. Tim Dyrby
Cand.med. Suzanne Granhøj Lindquist
Cand.med. Kieu Phungh
Cand.scient. Charlotte Ryberg
Cand.pharm. Anja Simonsen
Ergoterapeut, MPH, Lisbeth Villemoes
Sørensen
Cand.psyk. Asmus Vogel
Andre forskere
Overlæge Birgitte Bo Andersen
Læge Rachid Bech-Azeddine
Neuropsykolog Jytte Dock
Projektkoordinator Ane Eckermann
Cand.med., ph.d. Tina Vraamark
Elberling
Forskningspsykolog, cand.mag. Anders
Gade
1. reservelæge Peter Høgh
Overlæge Merete Hørding
Projektkoordinator Susanne Rishøj
Neuropsykolog Jette Stokholm
Øvrigt forskningspersonale
Forskningssygeplejerske Oda Jakobsen
Forskningssekretær Hanne M. Kiffer
Vigtigste satsningsområder
inden for forskningen
Klinisk demensforskning, epidemiologi,
patogenese, biomarkører og
neuroimaging, genetik, tidlig
diagnostik, behandling, jura og tidlig
social indsats.
Alzheimers sygdom.
Fronto-temporal demens.
Arvelige demenssygdomme.
Normaltrykshydrocephalus.
Publikationer
Disputatser og ph.d.-afhandlinger
forsvaret i året
Vogel A. Kognitive forstyrrelser ved
Alzheimers sygdom i tidlig fase
(ph.d.-afhandling). København: Eget
forlag; 2005:1-62. Forsvaret 16/12
2005 ved Københavns Universitet,
Det Samfundsvidenskabelige
Fakultet.
Videnskabelige artikler
A. Førsteforfatter fra
forskningsenheden
Bech-Azeddine R, Gjerris F, Waldemar
G, Czosnyka M, Juhler M.
Intraventricular or lumbar infusion
test in adult communicating
hydrocephalus? Practical
consequences and clinical outcome of
shunt operation. Acta Neurochir
(Wien) 2005;147(10):1027-36.
Stokholm J, Vogel A, Gade A, Waldemar
G. The executive interview as a
screening test for executive
dysfunction in patients with mild
dementia. J Am Geriatr Soc
2005;53(9):1577-81.
Stokholm J, Jakobsen O, Czarna JM,
Mortensen HV, Waldemar G. Years
of severe and isolated amnesia can
precede the development of dementia
in early-onset Alzheimer's disease.
Neurocase 2005;11(1):48-55.
Vogel A, Hasselbalch SG, Gade A,
Ziebell M, Waldemar G. Cognitive
and functional neuroimaging
correlate for anosognosia in mild
cognitive impairment and
Alzheimer's disease. Int J Geriatr
Psychiatry 2005;20(3):238-46.
Vogel A, Gade A, Stokholm J, Waldemar
G. Semantic memory impairment in
the earliest phases of Alzheimer's
disease. Dement Geriatr Cogn Disord
2005;19(2-3):75-81.
Waldemar G. Neurology. In: Burns A, ed.
Standards in Dementia Care. London:
Taylor & Francis; 2005:179-84.
Waldorff FB, Rishoj S, Waldemar G.
Identification and diagnostic
evaluation of possible dementia in
general practice. A prospective study.
Scand J Prim Health Care
2005;23(4):221-6.
B. Medforfatter fra forskningsenheden
Adams KH, Hansen ES, Pinborg LH,
Hasselbalch SG, Svarer C, Holm S,
Bolwig TG, Knudsen GM. Patients
with obsessive-compulsive disorder
have increased 5-HT2A receptor
binding in the caudate nuclei. Int J
Neuropsychopharmacol
2005;8(3):391-401.
Albert H, Hovmand B, Lund H, Winkel
L, Sørensen LV. Case rapport. En
grundbog i formidling. København:
Munksgaard Danmark; 2005.
Burns A, Ballard C, Banerjee S,
Calabrese P, de Deyn PP, Grossberg
G, et al. The clinical use of
Memantine. In: Vellas B, ed.
Research and Practice in Alzheimer's
Disease. Paris: Serdi; 2005:205-20.
Gjedde A, Johannsen P, Cold GE,
Ostergaard L. Cerebral metabolic
response to low blood flow: possible
role of cytochrome oxidase
inhibition. J Cereb Blood Flow Metab
2005;25(9):1183-96.
Jorgensen LM, Nielsen JE, Ravnborg M.
MEP recruitment curves in multiple
sclerosis and hereditary spastic
paraplegia. J Neurol Sci
2005;15;237(1-2):25-9.
Pantoni L, Basile AM, Pracucci G,
Asplund K, Bogousslavsky J,
Chabriat H, et al. Impact of agerelated
cerebral white matter changes
on the transition to disability -- the
LADIS study: rationale, design and
methodology. Neuroepidemiology
2005;24(1-2):51-62.
Ruetschi U, Zetterberg H, Podust VN,
Gottfries J, Li S, Hviid SA, et al.
Identification of CSF biomarkers for
frontotemporal dementia using
SELDI-TOF. Exp Neurol
2005;196(2):273-81.
Scheuer KH, Nielsen JE, Krabbe K,
Simonsen C, Koefoed P, Sorensen
SA, et al. Reduced regional cerebral
blood flow in SPG4-linked hereditary
spastic paraplegia. J Neurol Sci
2005;15;235(1-2):23-32.
Schmidt EA, Czosnyka Z, Momjian S,
Bech RA, Pickard J. Intracranial
baroflex yielding in early Cushing
repsons in human. Acta Neurochir
(suppl) 2005;95:253-6.
Skibinski G, Parkinson NJ, Brown JM,
Chakrabarti L, Lloyd SL, Hummerich
H, et al. Mutations in the endosomal
ESCRTIII-complex subunit
CHMP2B in frontotemporal
dementia. Nat Genet 2005;37(8):806-
8.
Stark AK, Pelvig DP, Jorgensen AM,
Andersen BB, Pakkenberg B.
Measuring morphological and
cellular changes in Alzheimer's
dementia: a review emphasizing
stereology. Curr Alzheimer Res
2005;2(4):449-81.
Svarer C, Madsen K, Hasselbalch SG,
Pinborg LH, Haugbol S, Frokjaer
VG, et al. MR-based automatic
delineation of volumes of interest in
human brain PET images using
probability maps. Neuroimage
2005;15;24(4):969-79.
Thellefsen T, Sørensen LV. Case study 2:
Vidensprofilering af et ikkevidenskabeligt
vidensdomæne: Dansk
ergoterapi. In: Thellefsen T, ed.
Vidensprofilering. Aalborg: Aalborg
Universitetsforlag; 2005:68-73.
van der Flier WM, van Straaten EC,
Barkhof F, Verdelho A, Madureira S,
Pantoni L, et al. Small vessel disease
and general cognitive function in
nondisabled elderly: the LADIS
study. Stroke 2005;36(10):2116-20.
Neurobiologisk
Forskningsenhed
Videnskabeligt personale
Seniorforskere
Biolog, ph.d. Susana Aznar
Overlæge, dr.med. Steen Hasselbalch
Civilingeniør, ph.d.-stud. Esben Høgh-
Rasmussen
Professor, dr.med. Gitte Moos Knudsen
Civilingeniør, ph.d. Finn Årup Nielsen
Professor, dr.med. Olaf B. Paulson
Civilingeniør, ph.d. Claus Svarer
Ph.d.-studerende
Cand.med. Daniela Balslev
Videnskabelig årsrapport 59