Videnskabelig årsrapport 2005 - Rigshospitalet

Diagnostisk Center
Inflammopharmacology 2005;13(1-
3):201-7.
Corlin DB, Sen JW, Ladefoged S, Lund
GB, Nissen MH, Heegaard NH.
Quantification of cleaved beta2-
microglobulin in serum from patients
undergoing chronic hemodialysis.
Clin Chem 2005;51(7):1177-84.
Csillag C, Nielsen OH, Borup R, Nielsen
FC. Hvor langt er vi fra klinisk brug
af array-teknologi? Ugeskr Læger
2005;167(20):2168-70.
Csillag C, Nielsen OH, Borup R, Nielsen
FC. Microarrays and Crohn's disease:
collectininformationg reliable. Scand
J Gastroenterol 2005;40(4):369-77.
Dahl M, Tybjaerg-Hansen A, Lange P,
Nordestgaard BG. Asthma and
COPD in cystic fibrosis intron-8 5T
carriers. A population-based study.
Respir Res 2005;6(1):113.
Ehrstrom M, Levin F, Kirchgessner AL,
Schmidt PT, Hilsted LM, Gryback P,
et al. Stimulatory effect of
endogenous orexin A on gastric
emptying and acid secretion
independent of gastrin. Regul Pept
2005;132(1-3):9-16.
Eidemark I, Szpirt W, Bro S.
Plasmaferese. In: Eidemark I, Bro S,
eds. Dialyse. Århus: FADL’s Forlag;
2005:287-94.
Ellervik C, Tybjaerg-Hansen A, Grande
P, Appleyard M, Nordestgaard BG.
Hereditary hemochromatosis and risk
of ischemic heart disease: a
prospective study and a case-control
study. Circulation 2005;112(2):185-
93.
Faurschou M, Kamp S, Cowland JB,
Udby L, Johnsen AH, Calafat J, et al.
Prodefensins are matrix proteins of
specific granules in human
neutrophils. J Leukoc Biol
2005;78(3):785-93.
Frederiksen J, Juul K, Tybjaerg-Hansen
A, Nordestgaard BG. Mendelian
randomization suggests that vascular
events cause hyperhomocystenemia,
rather than vice versa. Blood
2005;(105):3382-4.
Gatke MR, Viby-Mogensen J, Ostergaard
D, Bundgaard JR. Response to
mivacurium in patients carrying the k
variant in the butyrylcholinesterase
gene. Anesthesiology
2005;102(3):503-8.
Hudlebusch HR, Theilgaard-Monch K,
Lodahl M, Johnsen HE, Rasmussen
T. Identification of ID-1 as a
potential target gene of MMSET in
multiple myeloma. Br J Haematol
2005;130(5):700-8.
Jensen H, Yamamoto K, Bundgaard JR,
Rehfeld JF, Johnsen AH. Processing
of chicken progastrin at post-Phe
bonds by an aspartyl protease.
Biochim Biophys Acta
2005;1748(1):43-9.
Juul K, Tybjaerg-Hansen A, Marklund S,
Heegaard NH, Steffensen R, Sillesen
HH, et al. [Genetically determined
reduction in antioxidative protection
and increased risk of ischemic heart
disease--secondary publication].
Ugeskr Laeger 2005;167(7):767-70.
Juul K, Tybjaerg-Hansen A, Mortensen J,
Lange P, Vestbo J, Nordestgaard BG.
Factor V leiden homozygosity,
dyspnea, and reduced pulmonary
function. Arch Intern Med
2005;165(17):2032-6.
Knudsen TT, Thorsen S, Jensen SA,
Dalhoff K, Schmidt LE, Becker U, et
al. Effect of intravenous N-
acetylcysteine infusion on
haemostatic parameters in healthy
subjects. Gut 2005;54(4):515-21.
Levin F, Edholm T, Ehrstrom M, Wallin
B, Schmidt PT, Kirchgessner AM, et
al. Effect of peripherally
administered ghrelin on gastric
emptying and acid secretion in the
rat. Regul Pept 2005;131(1-3):59-65.
Milman N, Steig T, Koefoed P, Pedersen
P, Fenger K, Nielsen FC. Frequency
of the hemochromatosis HFE
mutations C282Y, H63D, and S65C
in blood donors in the Faroe Islands.
Ann Hematol 2005;84(3):146-9.
Moestrup SK, Nielsen LB. The role of the
kidney in lipid metabolism. Curr
Opin Lipidol 2005;16(3):301-6.
Moller F, Andersen CB, Nielsen LB.
Adhesion of T and B lymphocytes to
mouse atherosclerotic aortas:
association with lesion topology and
VCAM-1 expression. Scand J Clin
Lab Invest 2005;65(7):559-70.
Moller LB, Bukrinsky JT, Molgaard A,
Paulsen M, Lund C, Tumer Z, et al.
Identification and analysis of 21
novel disease-causing amino acid
substitutions in the conserved part of
ATP7A. Hum Mutat 2005;26(2):84-
93.
Moller LB, Paulsen M, Koch R, Moats R,
Guldberg P, Guttler F. Interindividual
variation in brain
phenylalanine concentration in
patients with PKU is not caused by
genetic variation in the 4F2hc/LAT1
complex. Mol Genet Metab 2005;86
Suppl 1:S119-23.
Moller LB, Romstad A, Paulsen M,
Hougaard P, Ormazabal A, Pineda M,
et al. Pre- and postnatal diagnosis of
tyrosine hydroxylase deficiency.
Prenat Diagn 2005;25(8):671-5.
Poulsen CB, Borup R, Nielsen FC,
Borregaard N, Hansen M, Gronbaek
K, Moller MB, Ralfkiaer E.
Microarray-based classification of
diffuse large B-cell lymphoma. Eur J
Haematol 2005;74(6):453-65
Poulsen CB, Penkowa M, Borup R,
Nielsen FC, Caceres M, Quintana A,
et al. Brain response to traumatic
brain injury in wild-type and
interleukin-6 knockout mice: a
microarray analysis. J Neurochem
2005;92(2):417-32.
Ripa RS, Katballe N, Wikman FP, Jager
AC, Bernstein I, Orntoft T, et al.
Presymptomatic diagnosis using a
deletion of a single codon in families
with hereditary non-polyposis
colorectal cancer. Mutat Res
2005;570(1):89-96.
Saldo M, Moller K, Friis-Hansen LJ.
Ekstrem anæmi udløst af en
hæmorragisk gastrointestinal
stromatumor. Ugeskr Læger
2005;167(4):407-9.
Schmidt PT, Naslund E, Gryback P,
Jacobsson H, Holst JJ, Hilsted L, et
al. A role for pancreatic polypeptide
in the regulation of gastric emptying
and short-term metabolic control. J
Clin Endocrinol Metab
2005;90(9):5241-6.
Sun YQ, Petersson F, Monstein HJ,
Soderholm JD, Rehfeld JF, Borch K.
Long-term morpho-functional
development of Helicobacter pyloriinduced
gastritis in Mongolian
gerbils. Scand J Gastroenterol
2005;40(10):1157-67.
Udby L, Lundwall A, Johnsen AH,
Fernlund P, Valtonen-Andre C, Blom
AM, et al. beta-Microseminoprotein
binds CRISP-3 in human seminal
plasma. Biochem Biophys Res
Commun 2005;333(2):555-61.
Venneman NG, Renooij W, Rehfeld JF,
VanBerge-Henegouwen GP, Go PM,
Broeders IA, et al. Small gallstones,
preserved gallbladder motility, and
fast crystallization are associated with
pancreatitis. Hepatology
2005;41(4):738-46.
Vinten J, Johnsen AH, Roepstorff P,
Harpoth J, Tranum-Jensen J.
Identification of a major protein on
the cytosolic face of caveolae.
Biochim Biophys Acta
2005;1717(1):34-40.
Weischenfeldt J, Lykke-Andersen J, Porse
BT. Messenger RNA surveillance:
neutralizing natural nonsense. Curr
Biol 2005;(15):R559-62.
Wang YZ, Goetze JP, Videbaek R,
Rehfeld JF, Kastrup J. Increased
circulating endothelins are not of
cardiopulmonary origin in heart
failure patients. Scand J Clin Lab
Invest 2005;65(4):341-7.
Zekri L, Chebli K, Tourriere H, Nielsen
FC, Hansen TV, Rami A, et al.
Control of fetal growth and neonatal
survival by the RasGAP-associated
endoribonuclease G3BP. Mol Cell
Biol 2005;25(19):8703-16.
C. Bidrag til multicenterforsøg og
lignende
Danesh J, Lewington S, Thompson SG,
Lowe GD, Collins R, Kostis JB, et al.
Plasma fibrinogen level and the risk
of major cardiovascular diseases and
nonvascular mortality: an individual
participant meta-analysis. JAMA
2005;294(14):1799-809.
Klinisk Farmakologisk
Afdeling Q
Videnskabeligt personale
Seniorforskere
Professor, overlæge, dr.med. Henrik
Enghusen Poulsen
Overlæge, dr.med. Kim Dalhoff
Ph.d.-studerende
Bente Glintborg
Peter René Hillestrøm
12 Videnskabelig årsrappport