Videnskabelig årsrapport 2005 - Rigshospitalet

Neurocentret
B. Medforfatter fra forskningsenheden
Fazekas F, Sorensen PS, Filippi M,
Ropele S, Lin X, Koelmel HW, et al.
MRI results from the European Study
on Intravenous Immunoglobulin in
Secondary Progressive Multiple
Sclerosis (ESIMS). Mult Scler
2005;11(4):433-40.
Freedman MS, Thompson EJ,
Deisenhammer F, Giovannoni G,
Grimsley G, Keir G, et al.
Recommended standard of
cerebrospinal fluid analysis in the
diagnosis of multiple sclerosis: a
consensus statement. Arch Neurol
2005;62(6):865-70.
Frohman EM, Stuve O, Havrdova E,
Corboy J, Achiron A, Zivadinov R, et
al. Therapeutic considerations for
disease progression in multiple
sclerosis: evidence, experience, and
future expectations. Arch Neurol
2005;62(10):1519-30.
Mathiesen HK, Tscherning T, Sorensen
PS, Larsson HB, Rostrup E, Paulson
OB, et al. Multi-slice echo-planar
spectroscopic MR imaging provides
both global and local metabolite
measures in multiple sclerosis. Magn
Reson Med 2005;53(4):750-9.
Roxburgh RH, Seaman SR, Masterman T,
Hensiek AE, Sawcer SJ, Vukusic S,
et al. Multiple Sclerosis Severity
Score: using disability and disease
duration to rate disease severity.
Neurology 2005;64(7):1144-51.
Sawcer S, Ban M, Maranian M, Yeo TW,
Compston A, Kirby A, et al. A highdensity
screen for linkage in multiple
sclerosis. Am J Hum Genet
2005;77(3):454-67.
Vaskulær og almen
neurologi
Videnskabeligt personale
Seniorforskere
Overlæge, dr.med. Peter Arlien-Søborg
Afdelingslæge Ingelise Christiansen
Klinikchef, overlæge, dr.med. Palle
Petersen
Neuropsykolog Annelise Smed
Neuropsykolog Hanne Udesen
Andre forskere
Læge Lena Hjermind
Læge Daniel Kondziella
Vigtigste satsningsområder
inden for forskningen
Cerebrovaskulære sygdomme.
Publikationer
Videnskabelige artikler
A. Førsteforfatter fra
forskningsenheden
Hjermind LE, Lokkegaard A, Werdelin
LM, Regeur L, Jespersen B, Madsen
FF, et al. Deep brain stimulation of
therapy-refractory, disabling
dystonia. Danish Society of
Movement Disorders (Danmodis).
Ugeskr Laeger 2005;167:1378.
Petersen P. Ximelagatran – a promising
new drug in thromboembolic
disorders. Curr Pharm Des
2005;11:527-38.
B. Medforfatter fra forskningsenheden
Albers GW, Diener HC, Frison L, Grind
M, Nevinson M, Partridge S, et al.
Ximelagatran vs warfarin for stroke
prevention in patients with
nonvalvular atrial fibrillation: a
randomized trial. JAMA
2005;293(6):690-8.
Asmus F, Salih F, Hjermind LE,
Ostergaard K, Munz M, Kuhn AA, et
al. Myoclonus-dystonia due to
genomic deletions in the epsilonsarcoglycan
gene. Ann Neurol
2005;58(5):792-7.
Brenner E, Kondziella D, Haberg A,
Sonnewald U. Impaired glutamine
metabolism in NMDA receptor
hypofunction induced by MK801. J
Neurochem 2005;94(6):1594-603.
Lindquist SG, Norremolle A, Hjermind
LE, Hasholt L, Nielsen JE. Meiotic
CAG repeat instability in
spinocerebellar ataxia type 6:
Maternally transmitted elongation in
a presumed sporadic case. J Neurol
Sci 2006;241(1-2):95-8.
Klinik for
Rygmarvsskader
Videnskabeligt personale
Seniorforskere
Overlæge, dr.med. Fin Biering-Sørensen
Overlæge, ph.d. Michael von Linstow
Ph.d.-studerende
Cand.scient. Klaus Klinge
Læge Ingeborg Beate Lidal
Sygeplejerske, cand.cur. Bente Martinsen
Læge Maja Mladenovic
Cand.scient. Rosa Winther
Vigtigste satsningsområder
inden for forskningen
Epidemiologiske undersøgelser.
Spasticitet/smerte/osteoporose hos
rygmarvsskadede.
Projekter om neuroprotektion på
rygmarvsskadet rottemodel.
Effektmålsundersøgelser.
Urologiske/mikrobiologiske projekter
relateret til rygmarvsskadede.
Publikationer
Videnskabelige artikler
A. Førsteforfatter fra
forskningsenheden
Biering-Sorensen F, Laeessoe L, Sonksen
J, Bagi P, Nielsen JB, Kristensen JK.
The effect of penile vibratory
stimulation on male fertility potential,
spasticity and neurogenic detrusor
overactivity in spinal cord lesioned
individuals. Acta Neurochir Suppl
2005;93:159-63.
Biering-Sorensen F. Evidence-based
medicine in treatment and
rehabilitation of spinal cord injured.
Spinal Cord 005;43(10):587-92.
Broholm B, Podenphant J, Biering-
Sorensen F. The course of bone
mineral density and biochemical
markers of bone turnover in early
postmenopausal spinal cord-lesioned
females. Spinal Cord
2005;43(11):674-7.
B. Medforfatter fra forskningsenheden
Finnerup NB, Biering-Sorensen F,
Johannesen IL, Terkelsen AJ, Juhl
GI, Kristensen AD, et al. Intravenous
lidocaine relieves spinal cord injury
pain: a randomized controlled trial.
Anesthesiology 2005;102(5):1023-
30.
Hansen J, Media S, Nohr M, Biering-
Sorensen F, Sinkjaer T, Rijkhoff NJ.
Treatment of neurogenic detrusor
overactivity in spinal cord injured
patients by conditional electrical
stimulation. J Urol
2005;173(6):2035-9.
Hansen NL, Conway BA, Halliday DM,
Hansen S, Pyndt HS, Biering-
Sorensen F, et al. Reduction of
common synaptic drive to ankle
dorsiflexor motoneurons during
walking in patients with spinal cord
lesion. J Neurophysiol
2005;94(2):934-42.
Lundgren-Nilsson A, Grimby G, Ring H,
Tesio L, Lawton G, Slade A, et al.
Cross-cultural validity of functional
independence measure items in
stroke: a study using Rasch analysis.
J Rehabil Med 2005;37(1):23-31.
Nowak M, Holm S, Biering-Sorensen F,
Secher NH, Friberg L. "Central
command" and insular activation
during attempted foot lifting in
paraplegic humans. Hum Brain Mapp
2005;25(2):259-65.
Vissing K, Andersen JL, Harridge SD,
Sandri C, Hartkopp A, Kjaer M, et al.
Gene expression of myogenic factors
and phenotype-specific markers in
electrically stimulated muscle of
paraplegics. J Appl Physiol
2005;99(1):164-72.
Psykiatrisk Klinik,
Neuropsykiatrisk
Laboratorium og
Sexologisk Klinik
Videnskabeligt personale
Seniorforskere
Overlæge Henrik Steen Andersen
Professor, dr.med. Tom G. Bolwig
Overlæge Henrik Dam
Overlæge, dr.med. Marianne Hertz
Lektor Ole Steen Jørgensen
Professor, dr.med. Lars Vedel Kessing
62 Videnskabelig årsrappport