Videnskabelig årsrapport 2005 - Rigshospitalet

Neurocentret
Neuromuskulær Klinik
Videnskabeligt personale
Seniorforskere
Overlæge Poul Brodersen
Afdelingslæge Ingelise Christiansen
1. reservelæge David Gaist
Overlæge, dr.med. Klaus Hansen
Seniorforsker Thomas Krag
Seniorforsker Zhuqing Qu Petersen
Overlæge, dr.med. John Vissing
Andre forskere
Klinisk assistent Susanne Tvede Andersen
Klinisk assistent Tina Dysgaard Jeppesen
Klinisk assistent Marie-Louise Sveen
Klinisk assistent Mette Cathrine Ørngreen
Studenterforskere
Stud.med. Simon Hauerslev
Øvrigt forskningspersonale
Danuata Goralska-Olsen
Eva Rahtkens
Vigtigste satsningsområder
inden for forskningen
Behandling og diagnostik af
muskelsygdomme og neuropatier.
Basalfysiologiske undersøgelser af
myopatier.
Publikationer
Videnskabelige artikler
A. Førsteforfatter fra
forskningsenheden
Anthonisen M, Toft R, Ronager J, Vissing
J. [Patient demographics and
evaluation of examinations in a
neuromuscular clinic over a threeyear
period]. Ugeskr Laeger
2005;167(22):2405-8.
Olsen DB, Orngreen MC, Vissing J.
Aerobic training improves exercise
performance in facioscapulohumeral
muscular dystrophy. Neurology
2005;64(6):1064-6.
Orngreen MC, Olsen DB, Vissing J.
Aerobic training in patients with
myotonic dystrophy type 1. Ann
Neurol 2005;57(5):754-7.
Orngreen MC, Duno M, Ejstrup R,
Christensen E, Schwartz M, Sacchetti
M, et al. Fuel utilization in subjects
with carnitine palmitoyltransferase 2
gene mutations. Ann Neurol
2005;57(1):60-6.
Vissing J, Quistorff B, Haller RG. Effect
of fuels on exercise capacity in
muscle phosphoglycerate mutase
deficiency. Arch Neurol
2005;62(9):1440-3.
B. Medforfatter fra forskningsenheden
Bogdanovich S, Perkins KJ, Krag TO,
Whittemore LA, Khurana TS.
Myostatin propeptide-mediated
amelioration of dystrophic
pathophysiology. FASEB J
2005;19(6):543-9.
Jorgensen LM, Nielsen JE, Ravnborg M.
MEP recruitment curves in multiple
sclerosis and hereditary spastic
paraplegia. J Neurol Sci 2005;237(1-
2):25-9.
Ostergaard E, Wibrand F, Orngreen MC,
Vissing J, Horn N. Impaired energy
metabolism and abnormal muscle
histology in mut- methylmalonic
aciduria. Neurology 2005;65(6):931-
3.
Scheuer KH, Nielsen JE, Krabbe K,
Simonsen C, Koefoed P, Sorensen
SA, et al. Reduced regional cerebral
blood flow in SPG4-linked hereditary
spastic paraplegia. J Neurol Sci
2005;235(1-2):23-32.
Schwartz M, Hertz JM, Sveen ML,
Vissing J. LGMD2I presenting with a
characteristic Duchenne or Becker
muscular dystrophy phenotype.
Neurology 2005;64(9):1635-7.
Dansk Multipel
Sclerose Center
(Inklusive Neuroimmunologisk
Laboratorium)
Videnskabeligt personale
Seniorforskere
Overlæge, ph.d. Morten Blinkenberg
Overlæge, dr.med. Susanne Helweg-
Larsen
Cand.scient., dr.med. Poul Erik
Hyldgaard Jensen
Cand.scient., ph.d. Signe Humle
Jørgensen
Chefpsykolog Agnete Jønsson
Afdelingslæge, ph.d. Annette Bang Oturai
Overlæge, dr.med. Mads Ravnborg
Afdelingslæge, ph.d. Finn Sellebjerg
Professor, dr.med. Per Soelberg Sørensen
Ph.d.-studerende
Læge Pameli Datta
Læge Martin Krakauer
Læge Thomas Tscherning
Andre forskere
Læge Jens Christian Faber-Rod
Læge Dan Hesse
Læge, cand.scient. Bodil Petersen
Øvrigt forskningspersonale
Bioanalytiker Henriette Egeblad
Forskningssygeplejerske Vibeke
Jespersen
Bioanalytiker Rikke Kroager
Forskningssekretær Annette Larsen
Specialestuderende Signe Limborg
Laborant Anne Marie Nordvig Petersen
Forskningssygeplejerske Joan Pietraszek
Laborant Louise Bonde Raasthøj
Forskningslaborant Susanne Velgaard
Vigtigste satsningsområder
inden for forskningen
Klinisk skleroseforskning.
Neuroimmunologisk forskning.
Neuropatologi ved sklerose.
Genetisk disposition til dissemineret
sklerose.
Billeddannelse ved dissemineret sklerose.
Rehabiliteringsforskning.
Neuropsykologiske aspekter ved
dissemineret sklerose.
Kliniske lægemiddelforsøg om
behandling af dissemineret sklerose.
Publikationer
Videnskabelige artikler
A. Førsteforfatter fra
forskningsenheden
Jorgensen LM, Nielsen JE, Ravnborg M.
MEP recruitment curves in multiple
sclerosis and hereditary spastic
paraplegia. J Neurol Sci 2005;237(1-
2):25-9.
Jorgensen SH, Jensen PE, Laursen H,
Sorensen PS. Intravenous
immunoglobulin ameliorates
experimental autoimmune
encephalomyelitis and reduces
neuropathological abnormalities
when administered prophylactically.
Neurol Res 2005;27(6):591-7.
Jorgensen SH, Sorensen PS. Intravenous
immunoglobulin treatment of
multiple sclerosis and its animal
model, experimental autoimmune
encephalomyelitis. J Neurol Sci
2005;233(1-2):61-5.
Ravnborg M, Blinkenberg M, Sellebjerg
F, Ballegaard M, Larsen SH,
Sorensen PS. Responsiveness of the
Multiple Sclerosis Impairment Scale
in comparison with the Expanded
Disability Status Scale. Mult Scler
2005;11(1):81-4.
Ravnborg MH. [Multiple sclerosis.
Danish Society of Multiple Sclerosis
Research (DAREMUS)]. Ugeskr
Laeger 2005;167(12-13):1405.
PM:15832725.
Sellebjerg F, Barnes D, Filippini G,
Midgard R, Montalban X, Rieckmann
P, et al. EFNS guideline on treatment
of multiple sclerosis relapses: report
of an EFNS task force on treatment
of multiple sclerosis relapses. Eur J
Neurol 2005;12(12):939-46.
Sellebjerg F, Ross C, Koch-Henriksen N,
Sorensen PS, Frederiksen JL,
Bendtzen K, et al. CD26 + CD4 + T
cell counts and attack risk in
interferon-treated multiple sclerosis.
Mult Scler 2005;11(6):641-5.
Sorensen PS, Deisenhammer F, Duda P,
Hohlfeld R, Myhr KM, Palace J, et
al. Guidelines on use of anti-IFN-beta
antibody measurements in multiple
sclerosis: report of an EFNS Task
Force on IFN-beta antibodies in
multiple sclerosis. Eur J Neurol
2005;12(11):817-27.
Sorensen PS. Multiple sclerosis:
pathophysiology revisited. Lancet
Neurol 2005;4(1):9-10.
Sorensen PS. The importance of NAb
testing in clinical practice.
Continuing Medical Education Series
2005;1:1-5.
Sorensen PS, Koch-Henriksen N, Ross C,
Clemmensen KM, Bendtzen K;
Danish Multiple Sclerosis Study
Group. Appearance and
disappearance of neutralizing
antibodies during interferon-beta
therapy. Neurology 2005;65(1):33-9.
Videnskabelig årsrapport 61