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Bio-medical Ontologies Maintenance and Change Management

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206 I.R. Godínez et al.<br />

Table 3. Algorithms Comparison<br />

Learning J. Ortega Baffes & Mooney Alpha-Beta<br />

Set [33] [34] Multimemories<br />

85/106 92.5% 93% 98%<br />

80/106 N/D N/D 98%<br />

70/106 N/D N/D 96%<br />

out of the 106 available(the rows labeled ”80/106” <strong>and</strong> ”70/106”). For each<br />

case, the procedure was repeated 100 times, taking into account the 20 best<br />

results, <strong>and</strong> calculating the maximum, minimum, <strong>and</strong> average percentage.<br />

The results are shown in table 4.<br />

Table 4. Algorithms Comparison<br />

ABMMC 85 training set 80 training set 70 training set<br />

Performance<br />

Maximum 98% 98% 96%<br />

Minimum 97% 96% 93%<br />

Average 97.45% 96.7% 94.55%<br />

4.2 DNA Splice-Junction Sequences Classification<br />

Our results are compared with R. Rampone [35] who presented an algorithm<br />

named BRAIN (Batch Relevance-based Artificial Intelligence). Two methodologies<br />

are used to compare the algorithms results: Hold-Out <strong>and</strong> 10-Fold<br />

Cross-Validation.<br />

4.2.1 Hold-Out<br />

The table 5 shows the result obtained in the experimental phase of the BRAIN<br />

algorithm where 2000 instances were taken for the training set <strong>and</strong> 1186 were<br />

left in the test set, leaving 4 repeated instances out of the experiment.<br />

The ABMMC algorithm is assessed under the following conditions: 2000<br />

instances were taken r<strong>and</strong>omly to create the training set <strong>and</strong> the remaining<br />

1190 were left in the test set. The procedure was repeated 20 times <strong>and</strong> the<br />

best result was chosen. In this case, the repetitions eliminated by Rampone<br />

are taken into account.<br />

Table 5. BRAIN Performance with Hold-Out Methodology<br />

Classes Instances for Instances for Number Error<br />

Training set Test set of Errors Rate<br />

EI 464 303 41/1186 3.4%<br />

IE 485 280 59/1186 4.9%

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