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Bio-medical Ontologies Maintenance and Change Management

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A Summary of Genomic Databases: Overview<br />

<strong>and</strong> Discussion<br />

Erika De Francesco 1 , Giuliana Di Santo 2 , Luigi Palopoli 2 ,<br />

<strong>and</strong> Simona E. Rombo 2<br />

1 Exeura, Via Pedro Alvares Cabrai, Edificio Manhattan,<br />

87036 C.da Lecco, Rende (CS), Italy<br />

erika.defrancesco@exeura.com<br />

2 Università della Calabria, Via Pietro Bucci 41c, 87036 Rende, Italy<br />

disanto@si.deis.unical.it, palopoli@deis.unical.it,<br />

simona.rombo@deis.unical.it<br />

Summary. In the last few years both the amount of electronically stored<br />

biological data <strong>and</strong> the number of biological data repositories grew up significantly<br />

(today, more than eight hundred can be counted thereof). In spite of<br />

the enormous amount of available resources, a user may be disoriented when<br />

he/she searches for specific data. Thus, the accurate analysis of biological<br />

data <strong>and</strong> repositories turn out to be useful to obtain a systematic view of biological<br />

database structures, tools <strong>and</strong> contents <strong>and</strong>, eventually, to facilitate<br />

the access <strong>and</strong> recovery of such data. In this chapter, we propose an analysis<br />

of genomic databases, which are databases of fundamental importance for<br />

the research in bioinformatics. In particular, we provide a small catalog of 74<br />

selected genomic databases, analyzed <strong>and</strong> classified by considering both their<br />

biological contents <strong>and</strong> their technical features (e.g, how they may be queried,<br />

the database schemas they are based on, the different data formats, etc.). We<br />

think that such a work may be an useful guide <strong>and</strong> reference for everyone<br />

needing to access <strong>and</strong> to retrieve information from genomic databases.<br />

1 The <strong>Bio</strong>logical Databases Scenario<br />

In such an evolving field like the biological one, having continuously new data<br />

to store <strong>and</strong> to analyze seems natural. Thus, the amount of data stored in<br />

biological databases is growing very quickly [12], <strong>and</strong> the number of relevant<br />

biological data sources can be nowadays estimated in about 968 units [34].<br />

The availability of so many data repositories is indisputably an important resource<br />

but, on the other h<strong>and</strong>, opens new quests, as to effectively access <strong>and</strong><br />

retrieve available data. Indeed, the distributed nature of biological knowledge,<br />

<strong>and</strong> the heterogeneity of biological data <strong>and</strong> sources, can often cause<br />

trouble to the user trying specific dem<strong>and</strong>s. And, in fact, not only such data<br />

sources are so numerous, but they use different kinds of representations, access<br />

methods <strong>and</strong> various features <strong>and</strong> formats are offered.<br />

A.S. Sidhu et al. (Eds.): <strong>Bio</strong><strong>medical</strong> Data <strong>and</strong> Applications, SCI 224, pp. 37–54.<br />

springerlink.com c○ Springer-Verlag Berlin Heidelberg 2009

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