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hand book for dental surgeons - Indian Dental Association ...

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Hand <strong>book</strong> <strong>for</strong> <strong>dental</strong> <strong>surgeons</strong> on <strong>dental</strong> management of persons with hemophilia and other haemostatic disorders<br />

The problem of <strong>dental</strong> extractions is a difficult one in hemophiliacs. Without proper premedication, even<br />

a minor surgical procedure may result in death from exsanguination. tooth extraction by means of rubber bands<br />

has often been used successfully, the rubber band being placed around the cervix of the tooth a nd allowed to<br />

migrate apically, causing exfoliation of the tooth through pressure necrosis of the periodontal ligament.<br />

Laboratory Findings. The characteristic defect of hemophilia is a prolonged coagulation time.<br />

the bleeding time is normal, as is the prothombin time and platelet agregation. In vitro, the deficiency of the<br />

clot-prompting factor in the plasma of hemophiliacs impairs clotting because it appears to retard development<br />

of the substance responsible <strong>for</strong> conversion of prothrombin to thrombin. Separation of the various <strong>for</strong>ms of<br />

hemophilia and proper diagnosis depends upon demonstration that the plasma of a patient with a known <strong>for</strong>m of<br />

hemophilia does not correct the plasma clotting defect in the patient under observation.<br />

Treatment and Prognosis. There is no known cure <strong>for</strong> hemophilia. the affected persons should be<br />

protected from traumatic injuries.<br />

If a surgical procedure such as tooth extraction must be carried out, the operation should be considered a<br />

major one and per<strong>for</strong>med only in a hospital.<br />

The greatest numbers of fatalities in hemophiliacs have resulted from surgical procedures, including<br />

tooth extraction. Preoperative transfusion of whole blood and the administration of antihemophilic factor<br />

concentrate are recommended. Nevertheless, oral surgery is a dangerous procedure and should be avoided<br />

whenever possible. Unfotunately, a small percentage of hemophiliacs have circulating anti-coagulant, probably<br />

an antibody, which specifically inactivates hemophilic factor, negating the effects of transfusion.<br />

The prognosis is variable, and many affected persons die during childhood.<br />

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Hand <strong>book</strong> <strong>for</strong> <strong>dental</strong> <strong>surgeons</strong> on <strong>dental</strong> management of persons with hemophilia and other haemostatic disorders

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