hand book for dental surgeons - Indian Dental Association ...

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Hand book for dental surgeons on dental management of persons with hemophilia and other haemostatic disorders
chromosomes (called X and Y) decide a person's sex. Females are born with two X-chromosomes (XX = girl).
Males
are born with one X and one Y chromosome (XY = boy).
Clot - A thick lump of blood formed by clotting factors that work together to help stop bleeding.
Cryoprecipitate - A treatment product made from blood plasma. It contains proteins, such as factor VIII (eight)
and von Willebrand factor, but not factor IX (nine). It is infused into a vein over a period of time. First
discovered
by Dr. Judith Graham Poole in 1965.
Asymptomatic carrier - A carrier who shows no outward signs of a condition.
Symptomatic carrier - A carrier who has low factor levels and manifests bleeding symptoms.
Coagulation disorders - a large group of conditions in which a person experiences excessive bleeding or
clotting.
Clotting factors - These are important proteins needed to form blood clots.
Desmopressin Acetate (also DDAVP or StimateÆ) - A synthetic hormone used to treat some people with mild
hemophilia or von Willebrand disease. The product increases the factor VIII levels or von Willebrand factor
levels in blood.
Diluent - The liquid that is mixed with factor concentrate powder. The final product is injected to treat bleeds.
Factor Assay - A specialized lab test used to determine the level of circulating factor VIII or IX in a personís
body. The test results are reported as a percentage of normal levels.
Factor deficiencies - These are rare disorders identified by the particular deficient or missing clotting factor in a
personís body. These conditions include: Factor I, II, V, VII, VIII, IX, X, XI, XII, and XIII.
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Hand book for dental surgeons on dental management of persons with hemophilia and other haemostatic disorders