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4 neWs<br />

test plant for CO 2 separation started up<br />

At the foot of the chimney of STEAG’s cogeneration plant in Herne, a ninemeter-high<br />

test plant has been built for evaluating new absorbents. The test<br />

plant, which is supposed to allow researchers to investigate absorbents for<br />

separating CO 2 from industrial and waste gases under real conditions, is part<br />

of the Efficient CO 2 Separation (EffiCO 2 ) Project of Creavis’ Science-to-<br />

Business Center Eco².<br />

<strong>Evonik</strong>’s business units are working together with experts from industry<br />

and science to develop new absorbents that should significantly reduce energy<br />

requirements for CO 2 separation. The aim is to investigate these new<br />

substances both under real conditions and in the laboratory. Over the next<br />

few weeks, the test plant will be tested for this purpose with commercially<br />

available absorption media to obtain a reference process for the new absorbents.<br />

For the investigations which are to occur under real conditions, the power<br />

plant has been built in such a way that part of the flue gas can be taken directly<br />

from the chimney and characterized by online analytics. The entire system<br />

has been made of glass to make it easy to view the process.<br />

Before the CO 2 is separated from the flue gas, interfering flue-gas components<br />

are removed in a scrubber column. Connected to this is the absorption<br />

column, in which the CO 2 contained in the flue gas is absorbed. In a<br />

third unit, the absorption medium is regenerated and pure CO 2 obtained,<br />

which is analyzed and returned to the chimney. The regenerated absorption<br />

medium is reconveyed to the absorption column and a continuous process is<br />

made possible. The EffiCO 2 project is funded by the German Federal Ministry<br />

of Education and Research (BMBF).<br />

A greenhouse gas, CO 2 is considered to be the single-most important<br />

cause of climate change. Global CO 2 emissions in 2010 amounted to more<br />

than 33 gigatons, an increase of about 30 percent over 1990. The energy<br />

sector emits the highest proportion of CO 2 . Because of mounting global<br />

energy requirements, the energy sector will continue in the future to account<br />

for a large share of CO 2 emissions. To meet energy requirements and simultaneously<br />

reduce CO 2 emissions, various CO 2 separation technologies are<br />

being developed and tested worldwide.<br />

BMBF PetrA project<br />

to simplify<br />

administration of<br />

biopharmaceuticals<br />

The goal of the interdisciplinary research project<br />

PeTrA*, which is sponsored by the<br />

German Federal Ministry of Education and<br />

Research (BMBF), is to remove the need for<br />

injections for biopharmaceuticals used for<br />

example in cancer immunotherapy by developing<br />

spray and tablet formulations which<br />

include innovative biofunctional polymers.<br />

The project is designed to simplify the administration<br />

of biopharmaceuticals and to improve<br />

their bioavailability. PeTrA is managed by a<br />

consortium consisting of <strong>Evonik</strong> Indus tries<br />

elements39 Issue 2|2012<br />

the nine-meter-high test<br />

plant for CO 2 separation<br />

AG, Merck KGaA, EMC microcollections<br />

GmbH (a hightech company for peptide and<br />

peptidomimetics synthesis), the Helmholtz<br />

Center for Infection Research (HZI), and the<br />

Fraunhofer Institute for Interfacial Engi neering<br />

and Biotechnology (IGB).<br />

The project, which started on July 1, 2011,<br />

is scheduled to last for three years Ap prox -<br />

imately half of the €6 million budget is supported<br />

by the three industry partners. The<br />

PeTrA consortium also includes the Friedrich<br />

Schiller University in Jena, Saarland University,<br />

the University of Nij megen (Neth erlands),<br />

Bonn University Hospital, the Charité<br />

Hospital Berlin, Kiel University, and Würzburg<br />

Uni versity.<br />

Biopharmaceuticals have been on the<br />

advance for years in modern drug therapy.<br />

They include peptides, proteins and antibodies,<br />

nucleic acids, and blood components, that<br />

all represent a promising basis for new active<br />

principles and for cancer immunotherapy.<br />

Many of these highly successful drugs im -<br />

prove patient life quality and have enormous<br />

technological potential for the pharmaceutical<br />

industry.<br />

Today, biopharmaceuticals are mostly<br />

administered by injection. Indeed, there is no<br />

efficient or broadly applicable system for<br />

administering them via the mouth (oral) or<br />

through the respiratory pathways (inhalation)<br />

because they are not easily absorbed by the<br />

mucous membranes of the gastrointestinal<br />

tract and respiration system, and tend to be<br />

degraded in the stomach before they can<br />

have an effect on the body. The PeTrA project<br />

aims at overcoming these obstacles by<br />

packaging highly sensitive biopharmaceuticals<br />

into nano- and micro-sized particles that<br />

transport the active ingredients through the<br />

mucous membranes and protect them from<br />

degradation in the stomach.

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