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AA. Gastric C I 06. ppt - Università degli studi di Pavia

AA. Gastric C I 06. ppt - Università degli studi di Pavia

AA. Gastric C I 06. ppt - Università degli studi di Pavia

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GASTRIC ADENOCARCINOMA<br />

* incidence and mortality rates markedly ↓ over past 70 yrs;<br />

- 1930: gastric cancer → 1st cause of cancer - related<br />

deaths in American men (by a factor of 2) and 3rd cause in<br />

women (behind tumors of uterine cervix and breast);<br />

- in USA, mortality dropped in men from 28 to 5.0 and in<br />

women from 27 to 2.3 / 100,000 population (↓ worldwide);<br />

* nonetheless, in 1996, 22,800 new cases <strong>di</strong>agnosed and<br />

11,800 pts <strong>di</strong>ed;<br />

* incidence varies widely among <strong>di</strong>fferent countries, being<br />

comparatively high in Japan, China, Chile, and Ireland (with<br />

still decreased incidence and mortality)

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