AA. Gastric C I 06. ppt - Università degli studi di Pavia

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Telomeres and telomerase * telomere = extension of DNA at chr ends, generated by telomerase reverse transcriptase (TERT, which uses an internally bound RNA loop as a template); [usually, “Hayflick limit” of ~ 50 - 70 division cycles for human diploid cells mediated by telomere length]
Schematic structure of telomere - repair complex and location of mutations * TERC, TERT, dyskerin, NOP10, NHP2 and GAR1 constitute telomerase ribo - nucleoprotein complex; * mutations of amino acids denoted by their single - letter codes Yamaguchi H et al N Engl J Med 2005; 352: 1413 - 24
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Università degli Studi di Pavia AA
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GASTRIC ADENOCARCINOMA
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GASTRIC ADENOCARCINOMA (Cancer Stat
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* age - adjusted cancer death rates
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RISK FACTORS AND PATHOGENESIS
Page 11 and 12: GASTRIC ADENOCARCINOMA Etiology. I.
Page 13 and 14: GASTRIC ADENOCARCINOMA Etiology. II
Page 15 and 16: NATURAL HISTORY OF HELICOBACTER PYL
Page 17 and 18: NATURAL HISTORY OF HELICOBACTER PYL
Page 19 and 20: Pathogen - host interactions in pat
Page 21 and 22: Pathogen - host interactions in pat
Page 23 and 24: GASTRIC ADENOCARCINOMA Etiology. II
Page 25 and 26: GASTRIC CANCER Pathology. I. * 85%
Page 27 and 28: GASTRIC CANCER Pathology. III. Leio
Page 30 and 31: GASTRIC ADENOCARCINOMA Pathology. V
Page 32 and 33: GASTRIC ADENOCARCINOMA Pathology. V
Page 34 and 35: GASTRIC ADENOCARCINOMA Pathology. I
Page 37 and 38: GASTRIC ADENOCARCINOMA Pathology. X
Page 47 and 48: “EARLY” GASTRIC CANCER
Page 55 and 56: GENETICS
Page 57 and 58: GASTRIC ADENOCARCINOMA Genetics. II
Page 59 and 60: GENETIC STEPS OF INTESTINAL TYPE GA
Page 61: GASTRIC ADENOCARCINOMA Genetics. II
Page 65 and 66: * adenoma → carcinoma sequence in
Page 67 and 68: GASTRIC ADENOCARCINOMA Genetics. VI
Page 71 and 72: RECEPTOR TYROSINE KINASE AND PROLIF
Page 73 and 74: SCHEMA TO GUIDE THE MANAGEMENT OF F
Page 77 and 78: CLINICAL FEATURES
Page 79 and 80: GASTRIC ADENOCARCINOMA Clinical fea
Page 81 and 82: GASTRIC ADENOCARCINOMA Clinical fea
Page 83: GASTRIC ADENOCARCINOMA Clinical fea
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AA. Gastric C I 06. ppt - Università degli studi di Pavia

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