Report in English with a Dutch summary (KCE reports 63A)

118 Breast Cancer KCE reports 63
Study ID Ref Search
date
McNeely ML
2006
Demark-
Wahnefried W
2006
Physical exercise after treatment of breast cancer.
[113] 2005 Women with early to
later stage (Stage 0–III)
breast cancer or who
had undergone breast
cancer surgery with or
without adjuvant
cancer
therapy
[260] NA Locoregionally staged
breast and prostate
cancer patients, who
were aged ≥ 65 years
old and within 18
months of diagnosis
Population Intervention Ouctomes Results Comments Study
type
Exercise (defined as a form of
leisure-time physical activity
that was performed on a
repeated basis over an
extended period of time, with
the intention of improving
fitness, performance or
health)
Intervention (n = 89):
telephone counseling and
tailored print materials aimed
at increased exercise and an
improved overall diet
(increased diet diversity with
increased F&Vs and whole
grains; decreased total fat,
saturated fat, and
cholesterol; and adequate iron
and calcium)
Control (n = 93): general
health counseling and materials.
Both interventions included 12
bimonthly 20- to 30-minute
sessions over a 6-month
period.
Exercise led to statistically significant
improvements in quality of life as assessed
by the Functional
Assessment of Cancer Therapy–General
(WMD 4.58, 95%CI 0.35 to
8.80) and Functional Assessment of Cancer
Therapy–Breast (WMD 6.62, 95%CI 1.21
to 12.03). Exercise also led to significant
improvements in physical functioning and
peak oxygen consumption and in reducing
symptoms of fatigue.
No significant differences between
treatment groups
14 RCTs included (4 of
high quality)
Randomization poorly
described
SR High
RCT Low
Level of
evidence