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Report in English with a Dutch summary (KCE reports 63A)

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<strong>KCE</strong> <strong>reports</strong> 63 Breast Cancer 59<br />

Diagnosis of breast cancer <strong>with</strong> triple test approach.<br />

Study ID Ref Search<br />

date<br />

Park JM 2003 [25] NA 19 patients <strong>with</strong> breast<br />

carc<strong>in</strong>oma and another<br />

nodule of 1 cm or less<br />

Population Intervention Outcomes Results Comments Study type Level of<br />

evidence<br />

(30 nodules)<br />

P<strong>in</strong>ero A 2003 [161] NA 43 patients <strong>with</strong> 45<br />

palpable breast lesions<br />

Shoma A 2006 [24] NA 124 consecutive<br />

patients <strong>with</strong> palpable<br />

breast cancer<br />

MeSH term(s) used: Breast Neoplasms/Diagnosis.<br />

Sonography<br />

Gold standard:<br />

histopathology<br />

Ultrasonography<br />

Gold standard:<br />

histopathology<br />

Cl<strong>in</strong>ical evaluation vs.<br />

mammography vs.<br />

sonography<br />

Gold standard:<br />

histopathology<br />

Tumour size<br />

measurement<br />

Sensitivity 100%<br />

Specificity 67%<br />

PPV 75%<br />

NPV 100%<br />

No <strong>in</strong>formation on<br />

diagnostic features<br />

US significantly more<br />

accurate<br />

Prospective<br />

cohort study<br />

Prospective<br />

cohort study<br />

Prospective<br />

cohort study<br />

Low<br />

Low<br />

Low

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