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Long-term Memory

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• Bilateral damage to the medial temporal lobes<br />

– Hippocampus<br />

• memory for events and episodes<br />

– Amygdala<br />

• memory for emotions<br />

– patient H.M. (1953)<br />

– sources of damage<br />

• Surgery, stroke, hypoxia, head injury<br />

• Korsakoff’s syndrome, Alzheimer’s disease<br />

• electroconvulsive therapy (ECT), benzodiazepines<br />

– anterograde and retrograde amnesia<br />

brain<br />

damage<br />

PAST PRESENT<br />

retrograde<br />

anterograde

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