C35. L. Rotiroti, E. De Tommasi, I. Ren<strong>di</strong>na, M. Canciello, G. Maglio, R. Palumbo, and L. De Stefano,” BIOACTIVE POLIMERS MODIFIED POROUS SILICON NANOSTRUCTURES”, 6th International Conference on Porous Semiconductuctors-Science and Technology, Poster presentation., Marzo 10-14, 2008, Mallorca, Spagna. C36. L. Rotiroti, P. Arcari, A. Lamberti, C. Sanges, E. De Tommasi, I. Rea, I. Ren<strong>di</strong>na and L. De Stefano “Optical detection of PNA-DNA hybri<strong>di</strong>zation in resonant porous silicon based devices” – Poster presentation. SPIE Photonics Europe, 2008, Strasbourg, France. C37. L. De Stefano, E. De Tommasi, I. Rea, L. Rotiroti, I. Ren<strong>di</strong>na “Porous Silicon resonant devices as optical transducers for nanostructured hybrid biosensors”, Invited, New Frontiers in Micro and Nano Photonics, 23-26 Aprile 2008, Firenze, Italia. C38. L. Rotiroti, I. Ren<strong>di</strong>na, E. De Tommasi, M. Canciello, G. Maglio, R. Palumbo, and L. De Stefano, “A nanostructured hybrid device based on polymers infiltrated porous silicon layers for biotechnological applications”, oral presentation, PPS-24 Meeting The Polymer Processing Society 24th Annual Meeting June 15-19, 2008, Salerno, ITALY. C39. E. De Tommasi, I. Rea, V. Di Sarno, L. Rotiroti, I. Ren<strong>di</strong>na and L. De Stefano “Porous silicon resonant mirrors in the high sensitive monitoring of biological interactions” – Oral presentation. First Me<strong>di</strong>terranean Photonics Conference of the European Optical Society, 2008, Ischia (Naples), Italy. C40. L. Rotiroti, I. Ren<strong>di</strong>na, E. De Tommasi, M. Canciello, G. Maglio, R. Palumbo, and L. De Stefano, A Hybrid Optical Biosensor Based on Polymer Infiltrated Porous Silicon Device, – Oral presentation, IEEE SENSORS 2008, Lecce (Italy). PATENTS Patent n. RM 2005 A 0002280 " An integrated device for the optical determination of the alcoholic content, in particular for wines and liquors, main procedures of fabrication, and main procedures of measurements" SCHOOLS AND WORKSHOPS: 1. 11 giugno 2008 SPETTROSCOPY SEMPLIFIED – THERMO FISCHER SCIENTIFIC, Hotel Selene, Pomezia 2. 6 febbraio 2008 LA BUONA PRATICA DI PESATA - GWP®, METTLER TOLEDO, Holiday Inn, Napoli. 3. 17 luglio 2007 MICROSCOPIA A SONDA NELLA SCIENZA DEI MATERIALI, seminario indetto da 2M STRUMENTI “Veeco”, Portici (Napoli). 4. 26 febbraio-2 marzo 2007 ADVANCED COURSE in design, synthesis, analysis and evaluation of bioactive molecules, Napoli. 5. 5-6 Luglio 2006 Ciclo <strong>di</strong> seminari sulla Luce <strong>di</strong> Sincrotrone, Napoli. 6. 26-27 giugno 2006 corso “ENZIMI DA IPERTERMOFILI E NANOTECNOLOGIE: ASPETTI APPLICATIVI”, Napoli. 7. 19-21 Giugno 2006 scuola <strong>di</strong> <strong>dottorato</strong> del Gruppo Elettronica (GE 2006), Benevento (BN), Italia. 8. 15-17 maggio 2006 corso teorico/pratico “FUNZIONALIZZAZIONE DI SUPERFICI VIA PLASMA PER APPLICAZIONI BIOTECNOLOGICHE”, Napoli. 9. 12 marzo 2006 Short Course “5 th International Conference on Porous Semiconductuctors- Science and Technology”, Sitges-Barcellona, Spagna.
Appen<strong>di</strong>x
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BIOCHIP AND LAB-ON-CHIP FOR GENOMIC
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The most beautiful thing we can exp
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SUMMARY There is no other inorganic
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commerciale di questi dispositivi
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del silicio coinvolge due portatori
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I sensori ottici basati sul silicio
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Si H OH O2 5% APTES Si H SiO2 OH 15
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verificare la sua capacità di lega
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60% al di sopra della superficie oc
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consente di inviare luce e convogli
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Introduction The development of bio
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mediators on biochips. Numerous tra
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The basic method to fabricate PSi i
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modulating the applied current duri
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PSi optical sensors are based on ch
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Figure 6. SEM images of different P
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Reflectivity (a.u.) 160 140 120 100
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23. Anderson SHC, Elliot H, Wallis
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phys. stat. sol. (c) 4, No. 6, 1966
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1968 L. De Stefano et al.: Optical
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1970 L. De Stefano et al.: Optical
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Introduction to the sensing mechani
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phys. stat. sol. (c) 4, No. 6, 1941
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phys. stat. sol. (c) 4, No. 6 (2007
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phys. stat. sol. (c) 4, No. 6 (2007
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Introduction: Porous Silicon surfac
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• Oxidation of porous silicon Wit
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DNA Optical Detection Based on Poro
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Sensors 2007, 6 membrane, cell, and
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Sensors 2007, 6 3. Results and Disc
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Sensors 2007, 6 graph we can also e
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Sensors 2007, 6 4. De Stefano, L.;
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Glutamine-Binding Protein from Esch
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GlnBP Binds Wheat Gliadin Toxic Seq
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GlnBP Binds Wheat Gliadin Toxic Seq
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S2020 SD’Auriaet al Fluorescence
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S2022 SD’Auriaet al Phase angle (
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S2024 SD’Auriaet al Fluorescence
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S2026 SD’Auriaet al (a) (b) ∆nd
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S2028 SD’Auriaet al [36] Szmacins
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Introduction: proteins from extremo
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Figure 2. Experimental setup used t
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Chemical and biological functionali
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Oligonucleotides direct synthesis o
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cm -1 (Si-O-Si) and 1065, 880 cm -1
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Abstract Physica E 38 (2007) 188-19
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190 surface through Si-C bonds. We
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