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Sensors 2008 8 2. Pacholski C.; Sartor M.; Sailor M. J.; Cunin F.; Miskelly G. M. Biosensing using porous silicon double-layer interferometers: Reflective interferometric fourier transform spectroscopy. J. Am. Chem. Soc. 2005, 127, 11636-11645. 3. De Stefano, L.; Rotiroti, L.; Rea, I.; Rendina, I.; Moretti, L.; Di Francia, G.; Massera, E.; Lamberti, A.; Arcari, P.; Sangez, C. Porous silicon-based optical biochips. J. Opt. A-Pure Appl. Op. 2006, 8, S540-S544. 4. Lee, M.R.; Fauchet, P.M. Two-dimensional silicon photonic crystal based biosensing platform for protein detection. Opt. Express 2007, 15, 4530-4535. 5. Cush, R.; Cronin, J.M.; Stewart, W.J.; Maule, C.H.; Molloy, J.; Goddard, N.J. The resonant mirror: a novel optical biosensor for direct sensing of biomolecular interactions. I: Principle of operation and associated instrumentation. Biosens Bioelectron. 1993, 8, 347-353. 6. Baldini, F.; Chester, A.N.; Homola, J.; Martellucci, S. Optical Chemical Sensors. Springer: Dordrecht, The Netherlands, 2006. 7. Chapron, J.; Alekseev, S.A.; Lysenko, V.; Zaitsev, V.N.; Barbier, D. Analysis of interaction between chemical agents and porous Si nanostructures using optical sensing properties of infra-red Rugate filters. Sensor. Actuat. B-Chem. 2007, 120, 706-711. 8. Ouyang, H.; Chrtistophersen, M.; Viard, R.; Miller, B.L.; Fauchet, P.M. Macroporous silicon microcavities for macromolecule detection. Adv. Funct. Mater. 2005, 15, 1851-1859. 9. Saarinen, J.J.; Weiss, S.M.; Fauchet, P.M.; Sipe, J.E. Optical sensor based on resonant porous silicon structures. Opt. Express 2005, 13, 3754-3764. 10. Khardani, M.; Bouaïcha, M.; Bessaïs, B. Bruggeman effective medium approach for modelling optical properties of porous silicon: comparison with experiment. Phys. Stat. Sol. 2007, 4, 1986- 1990. 11. Pirasteh, P.; Charrier, J.; Dumeige, Y.; Haesaert, S.; Joubert P. Optical loss of porous silicon and oxidized porous silicon planar waveguides. J. Appl. Phys. 2007, 101, 083110. 12. Ulrich, R.; Torge, R. Measurement of thin film parameters with a prism coupler. Appl. Optics 1973, 12, 2901-2908. 13. Rong, G.; Najmaie, A.; Sipe, J. E.; Weiss, S. M. Nanoscale porous silicon waveguide for label-free DNA sensing. Biosens. Bioelectron. 2008, 23, 1572-1576. 14. Descrovi, E.; Frascella, F.; Sciacca, B.; Geobaldo, F.; Dominici, L.; Michelotti, F. Coupling of surface waves in highly defined one-dimensional porous silicon photonic crystals for gas sensing applications. Appl. Phys. Lett. 2007, 91, 241109. © 2008 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
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BIOCHIP AND LAB-ON-CHIP FOR GENOMIC
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The most beautiful thing we can exp
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SUMMARY There is no other inorganic
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commerciale di questi dispositivi
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del silicio coinvolge due portatori
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I sensori ottici basati sul silicio
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Si H OH O2 5% APTES Si H SiO2 OH 15
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verificare la sua capacità di lega
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60% al di sopra della superficie oc
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consente di inviare luce e convogli
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Introduction The development of bio
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mediators on biochips. Numerous tra
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The basic method to fabricate PSi i
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modulating the applied current duri
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PSi optical sensors are based on ch
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Figure 6. SEM images of different P
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Reflectivity (a.u.) 160 140 120 100
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23. Anderson SHC, Elliot H, Wallis
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phys. stat. sol. (c) 4, No. 6, 1966
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1968 L. De Stefano et al.: Optical
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1970 L. De Stefano et al.: Optical
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Introduction to the sensing mechani
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phys. stat. sol. (c) 4, No. 6, 1941
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phys. stat. sol. (c) 4, No. 6 (2007
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phys. stat. sol. (c) 4, No. 6 (2007
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Introduction: Porous Silicon surfac
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• Oxidation of porous silicon Wit
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DNA Optical Detection Based on Poro
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Sensors 2007, 6 membrane, cell, and
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Sensors 2007, 6 3. Results and Disc
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Sensors 2007, 6 graph we can also e
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Sensors 2007, 6 4. De Stefano, L.;
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Glutamine-Binding Protein from Esch
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GlnBP Binds Wheat Gliadin Toxic Seq
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GlnBP Binds Wheat Gliadin Toxic Seq
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S2020 SD’Auriaet al Fluorescence
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S2022 SD’Auriaet al Phase angle (
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S2024 SD’Auriaet al Fluorescence
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S2026 SD’Auriaet al (a) (b) ∆nd
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S2028 SD’Auriaet al [36] Szmacins
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Introduction: proteins from extremo
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Figure 2. Experimental setup used t
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Chemical and biological functionali
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Oligonucleotides direct synthesis o
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cm -1 (Si-O-Si) and 1065, 880 cm -1
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Abstract Physica E 38 (2007) 188-19
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190 surface through Si-C bonds. We
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192 Acknowledgments The authors are
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Introduction: PSi hybrid systems Mu
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8. S.H.C. Anderson, H. Elliot, D.J.
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A polymer modified PSi optical devi
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The polymer solutions were prepared
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solution of 5(6)-Carboxyfluorescein
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5 CREATED USING THE RSC ARTICLE TEM
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5 10 15 20 25 30 35 The HFB biofilm
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5 10 15 20 25 Conclusions We have d
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Introduction to Lab-on-chip technol
Page 127 and 128: • Glass etching The technology fo
Page 129 and 130: Many lab-on-chip applications have
Page 131 and 132: Microsystems Based on Porous Silico
Page 133 and 134: Sensors 2006, 6 681 optical microca
Page 135 and 136: Sensors 2006, 6 683 changed with a
Page 137 and 138: Sensors 2006, 6 685 probably exists
Page 139 and 140: Sensors 2006, 6 687 6. Obermeier, E
Page 141 and 142: LASER OXIDATION MICROPATTERNING OF
Page 143 and 144: 384 48mW, using a setup composed of
Page 145 and 146: 386 APO fluorescence macroscopy sys
Page 147 and 148: PUBLICATIONS: J1. Luca De Stefano,
Page 149 and 150: P12. L. De Stefano, L. Rotiroti, I.
Page 151 and 152: C18. L. De Stefano, I. Rea, L. Roti
Page 153 and 154: Appendix
Page 155 and 156: White light source Gas channels Sea
Page 157 and 158: % Reflectance 110 100 90 80 70 60 5
Page 159 and 160: IOP PUBLISHING JOURNAL OF PHYSICS:
Page 161 and 162: J. Phys.: Condens. Matter 19 (2007)
Page 167 and 168: with a number of other sugar-bindin
Page 169 and 170: treatment in the range 600-800 nm,
Page 171 and 172: Sensors 2008, 8, 1-x manuscripts; D
Page 173 and 174: Sensors 2008 3 2. Experimental A hi
Page 175 and 176: Sensors 2008 5 Figure 3. Resonant p
Page 177: Sensors 2008 7 Figure 6. Resonance
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