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Immunotherapy Safety for the Primary Care ... - U.S. Coast Guard

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Pathophysiology<br />

• The physiologic effects of <strong>the</strong> pre-<strong>for</strong>med<br />

mediators define <strong>the</strong> early phase anaphylactic<br />

reaction,<br />

• While those of <strong>the</strong> syn<strong>the</strong>sized cytokine IL-4,<br />

IL-5, IL-13, and chemokines shape <strong>the</strong> late<br />

phase inflammatory reaction.

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