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Immunotherapy Safety for the Primary Care ... - U.S. Coast Guard

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<strong>Immuno<strong>the</strong>rapy</strong> Phases<br />

• Maintenance concentration = <strong>the</strong>rapeutically effective dose<br />

as determined by <strong>the</strong> Allergist<br />

• Build up phase (vials up to & including maintenance vial)<br />

– Involves receiving injections of increasing amounts of allergen(s)<br />

– Frequency of injections ranges from 1 - 2 times a week, although<br />

more rapid build-up schedules are possible.<br />

– The duration of this phase generally ranges from 3 to 6 months,<br />

depending upon <strong>the</strong> frequency of <strong>the</strong> 18-27 injections.<br />

• Maintenance phase (maintenance vial)<br />

– Begins when <strong>the</strong> effective <strong>the</strong>rapeutic dose is reached.<br />

– Differs <strong>for</strong> each person, depending on <strong>the</strong>ir level of allergen<br />

sensitivity (how 'allergic’ <strong>the</strong>y are to <strong>the</strong> allergens in <strong>the</strong>ir vaccine)<br />

and <strong>the</strong>ir response to <strong>the</strong> build-up phase.<br />

– The intervals between maintenance immuno<strong>the</strong>rapy injections<br />

generally ranges from 2 to 4 weeks (3-4 weeks).<br />

– Administered <strong>for</strong> 3-5 years.<br />

• AIT schedules ≠ VIT schedules

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