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Immunotherapy Safety for the Primary Care ... - U.S. Coast Guard

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Summary<br />

• Anaphylaxis: release of inflammatory mediators<br />

from mast cells & basophils (IgE-/non-IgE-mediated)<br />

• Symptoms: within minutes of exposure to<br />

triggering agent (less commonly can be delayed or biphasic)<br />

• Common triggers: drugs, foods, hymenoptera<br />

stings; idiopathic<br />

• First-line of treatment: injected epinephrine<br />

• Management: education and prevention

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