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These inconsistencies suggest that patients at low complication risk (without<br />

relevant deformities) can use common footwear (well adjusted, and of good quality)<br />

while patients with severe foot deformities could benefit from therapeutic<br />

footwear (247).<br />

Evidence summary<br />

II<br />

II<br />

II<br />

II<br />

The monofilament test has a sensitivity which ranges from 66% to 91% and a specificity<br />

that ranges from 34% to 86% to predict ulcer risk (247).<br />

The tuning fork is more inaccurate and has a lower predictive capacity for ulcer risk<br />

than the monofilament (247; 248).<br />

Biotensiometer: a vibration threshold over 25V has an 83% of sensitivity, 63% of specificity,<br />

a 2.2 +LH and a 0.27 –LH to predict foot ulcer after four years (247).<br />

In patients with symptoms which suggest the existence of PAD, the findings of absence<br />

of iliac, femoral or popliteal murmurs, normal pulse, as well as the combination of<br />

these symptoms, are useful to discard the disease (249).<br />

II The ankle-arm index of 0.90 or less suggests peripheral arterial disease (247).<br />

1+ Screening within a foot care structured program reduces ulcers and minor amputations<br />

slightly, and major amputations after two years significantly; in patients with ulcers, the<br />

evolution to amputations decreases (250).<br />

2+ In contexts different to the one presented in this guideline (252; 253), the programs<br />

which include screening, risk stratification and preventive and treatment measures depending<br />

on the risk, have managed to reduce the incidence of amputations.<br />

1+ There is limited evidence that education addressed to the patient can improve his<br />

knowledge about foot care and his attitude. In a trial carried out in patients at high risk,<br />

education reduced ulcer and amputation incidences after a year. Other studies have not<br />

stated any benefits (254).<br />

2+/3 Smoking is an amputation risk indicator (247).<br />

1+ The UKPDS study proved that intensive glycemic control was effective to reduce microvascular<br />

complications and led to the reduction of amputations (106).<br />

1+/2+ Therapeutic footwear and orthopaedic material can reduce the incidence of ulceration<br />

in patients at risk with prior ulcers and severe foot deformities (255; 256).<br />

Recommendations<br />

A<br />

D CPG<br />

Screening, risk stratification and foot at risk prevention and treatment-structured programs<br />

are recommended for diabetic patients.<br />

The professional staff that attends diabetic patients should assess the risk to develop<br />

diabetic foot in the control visits. Annual revision is recommended for patients at low<br />

risk, every three to six months for patients at moderate risk and every one to three<br />

months for high-risk patients.<br />

104 CLINICAL PRACTICE GUIDELINES IN THE NHS

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