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duration and intensity). Performing aerobic and anaerobic intensity exercise improved<br />

glycemic control (0.51% and 0.38% of HbA 1<br />

c reductions) in comparison<br />

to the control group, respectively), though the improvement was better when both<br />

were combined (additional 0.<strong>46</strong>% reduction).<br />

The group assigned to the aerobic intensity training showed a higher weight<br />

reduction as well as BMI reduction in comparison with the control group; the<br />

combination of both types of exercise was not higher than that in each of the<br />

interventions performed individually. The adverse effects were more frequent in<br />

those patients who did exercise (musculoskeletal pain or traumatisms), though no<br />

differences were observed as regards the hypoglycaemia stages. Although it is a<br />

high quality trial, it does present extrapolation problems to other contexts.<br />

The effects of exercise on morbimortality have been assessed in several<br />

long-term cohort studies involving a wide range of population groups (99-103).<br />

The inclusion criteria are variable as regards risk factors, cardiovascular disease<br />

antecedents or pharmacological treatments followed. The interventions vary as<br />

regards type and intensity of the exercise performed. The performance of continuous<br />

aerobic physical exercise for more than 120 minutes per week reduces the risk<br />

of coronary and cerebrovascular disease, both in women (100) and men (103).<br />

Improved physical condition, associated with higher exercise intensity reduces<br />

death risk (101), regardless of the obesity level (99).<br />

Cohort<br />

studies<br />

2+<br />

Evidence summary<br />

2+ Physical exercise performed on a regular basis reduces the risk of coronary and cerebrovascular<br />

disease (100; 103). Improved physical condition, associated with higher exercise<br />

intensity reduces death risk (101), regardless of the obesity level (99).<br />

1+ The aerobic and anaerobic intensity physical exercise programs are effective to improve<br />

glycemic control (0.6% of HbA 1<br />

c reductions) and can improve the response to insulin<br />

and TG levels (97; 98).<br />

1++ In DM 2 patients who are motivated and without severe complications, the combination<br />

of aerobic and anaerobic intensity exercise is higher in each of the modalities individually<br />

as regards the improvement of glycemic control (98).<br />

1+ Most of the interventions consist of three sessions per week in non-consecutive days; the<br />

exercise is performed under supervision and gradually (97; 98).<br />

Recommendations<br />

A<br />

DM 2 patients are recommended to perform regular and continuous aerobic and anaerobic<br />

intensive physical exercise, or preferably a combination of both. The recommended<br />

frequency is three weekly sessions on alternate days, gradual as regards duration and<br />

intensity and preferably, under supervision.<br />

58 CLINICAL PRACTICE GUIDELINES IN THE NHS

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