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Appendix 6. Assessment of macro- and microangiopathy<br />

in the diagnose and follow-up of DM 2<br />

Diagnosis<br />

CV Risk:<br />

BP, CT, TG, HDL,<br />

HbA 1 c, Tobacco<br />

Initial assessment of macro/microangiopathy<br />

Nephropathy:<br />

Albumin / creatinine<br />

ratio (mg/g)<br />

Diabetic foot:<br />

Monofi lament, AA Index a ,<br />

Foot and footwear inspection,<br />

symptoms<br />

Ocular:<br />

OF b<br />

CVR c ≥10%<br />

after 3-6 months<br />

with modification<br />

of lifestyle<br />

PAS ≥140<br />

PAD ≥80<br />

30-299<br />

Education and assessment<br />

of ulcer risk<br />

General care<br />

Statins<br />

Assess<br />

aspirin<br />

ACE<br />

inhibitors<br />

or<br />

Diuretic<br />

Energy<br />

multifactorial<br />

intervention d<br />

Risk<br />

Low<br />

Increases<br />

High e<br />

Ulcerate e<br />

Control<br />

Annual<br />

3-6 months<br />

1-3 months<br />

Individual<br />

CVR c ≥10% SBP ≥140<br />

30-299<br />

Diabetes evolution DBP ≥80<br />

>15 years Education and assessment<br />

of ulcer risk<br />

General care<br />

Retinopathy<br />

No<br />

Non-proliferative<br />

Proliferative<br />

Control<br />

3 years<br />

2 years<br />

Individual<br />

Follow-up<br />

CV Risk:<br />

BP, CT, TG, HDL,<br />

HbA 1<br />

c, Tobacco<br />

Nephropathy:<br />

Albumin / creatinine<br />

ratio (mg/g)<br />

Diabetic foot:<br />

Monofi lament, AA Index a ,<br />

Foot and footwear inspection,<br />

symptoms<br />

Annual assessment of macro/microangiopathy<br />

Ocular:<br />

OF b<br />

a<br />

AA Index (ankle-arm): in case of abnormal physical examination or another macro/microangiopathic disorder.<br />

b<br />

OF (ocular fundus): non-mydriatic camera or ophthalmologic consultation if there is no camera available.<br />

c<br />

CVR (cardiovascular risk): estimate according to the REGICOR table.<br />

d<br />

Diet, exercise, anti-tobacco therapy, ACE-inhibitors, aspirin, therapeutic target: SBP £130 mmHg, intensive HbA 1<br />

c and<br />

cholesterol control.<br />

e<br />

Requires assessment by specialized staff or, if available, foot unit staff or chiropodist.<br />

BP, SBP, DBP: blood pressure, systolic blood pressure, diastolic blood pressure; ; OF: ocular fundus; CT: cholesterol; TG:<br />

triglycerides.<br />

CLINICAL PRACTICE GUIDELINE ON TYPE 2 DIABETES 145

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