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Table of Contents
Presentation 9
Authors and collaborations 11
Questions to be answered 13
Summary of recommendations 17
1. Introduction 25
2. Scope and objectives 27
3. Methodology 29
4. Epidemiology and sanitary impact of type 2 diabetes mellitus 31
4.1. Epidemiology of DM 2 31
4.2. Costs for DM 2 32
4.3. Organization and assistance to DM 2 patients in the Spanish
National Health System 32
5. Definition, natural history, criteria, diagnoses and screening of DM 2 35
5.1. Defi nition of diabetes mellitus 35
5.2. Risk factors for the development of diabetes 36
5.2.1. Age and sex 36
5.2.2. Race 36
5.2.3. Genetic susceptibility 36
5.2.4. Gestational diabetes 36
5.2.5. Low weight at birth 37
5.2.6. Breast-feeding 37
5.2.7. Obesity 37
5.2.8. Diet and alcohol 38
5.2.9. Physical activity 39
5.2.10. Tobacco 39
5.2.11. Polycystic ovary syndrome 39
5.2.12. Heart failure 40
5.2.13. Drugs 40
5.3. DM 2 diagnosis 41
5.3.1. Diagnostic criteria 41
5.3.2. Diagnostic methods 42
5.4. DM 2 screening 44
6. Diabetes prevention in patients with intermediate hyperglycaemia 47
6.1. Impaired Fating Glucoseucose (IFG) 48
CLINICAL PRACTICE GUIDELINE ON TYPE 2 DIABETES 5