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ITEM NO.19 – HIGH THROUGHPUT SNP GENOTYPING AND GENE EXPRESSION SYSTEM, QTY: 1 NO. (FILE REF: 34/CCMB/APP/416/P12) SPECIFICATIONS FOR SNP GENOTYPING AND GENE EXPRESSION SYSTEM: High Throughput SNP Genotyping and Gene expression system for the following applications with technical specifications, features and accessories as below: Applications: Genome wide genotyping and custom genotyping. Whole genome gene expression. Whole genome methylation analysis. CNV analysis. Next Generation Sequencing. Specifications and Features: Dual laser excitation source and optics for scanning high density arrays with high resolution, fast scan times and to produce high quality reproducible data. Scanner resolution should be 0.3 micron or better. Should be able to scan different types of arrays/chips with fast scan times ranging from 1 minute to 15 minutes. The system should include a Hybridization unit, fluidics station and autoloader for processing and scanning the arrays/chips. The system should be upgradable to Next Generation Sequencing platform with integrated fluidics providing the flexibility of having sequencing and array technologies on one platform. Should be able to transit between array based and sequencing based gene expression analysis. Platform should be amenable for assay automation. The scanner should be the latest technology and should be able to carry out sensitive, rapid and accurate imaging of array/chips. The system should be modular and configurable for any level of throughput required. The system should include the basic control software and suitable analysis software (minimum of 5 user licenses) for all the above mentioned applications. Complete set of accessories needed for processing the arrays/chips for all the applications to be offered. The system offered should be the latest and advanced version having all the specifications and features mentioned above and should be of use for CCMB’s research programs for the next eight years or more. Scientific papers, references in reputed journals where the offered model has been used for the stated applications in the world (for the last three years or more) should be enclosed. To offer optionally: Upgrade for Next Generation Sequencing platform including suitable fluidics, kits and reagents and required software for control and data analysis. Liquid handling accessory for assay automation of array /chips with required consumables, reagents, software etc. Pre arrayed and custom array /chips for the above applications. Kits, reagents other accessories needed for all the above applications. Required servers/ workstations for downstream data analysis. Important clauses: BID DOCUMENT (YC) Page 62 of 63
Main system including subsystems, computers and accessories should operate on 220V, 50 Hz mains power. The computers / workstations and printers offered along with the system should be the latest model (configuration to be specified) compatible with the control and analysis software. Required interface cards, cables, CD writer etc to be included. The PC /workstation should have a three year comprehensive onsite Warranty. Detailed literatures (all originals) with technical specifications and features to be sent along with the offer. Detailed instruction and service manuals with circuit diagrams and all engineering details for the entire system should be supplied with the unit. Commitment to this clause to be made in the offer. Software supplied should be the latest versions and any upgradation in the software to be given free of cost for three years. Required calibration kits for the installation and testing should be supplied with the system. If required demonstration of the unit to be given at any installed sites in India. All standard accessories that would be supplied along with the unit should be clearly mentioned in the offer. Other required accessories should be offered as optionally. Essential electronic, mechanical spares and consumables to be offered for a minimum period of six months of operation. Detailed list of such items to be given separately. Complete installation and testing the equipment to its specifications should be done at the site of installation free of cost. After the installation, the system should be demonstrated to the users and samples should be run on the instrument and tested. User training to be given at site and periodic application training to be given till the users are familiar with the system and software. Commitment to this effect to be made in the offer Cost offered should include a two-year warranty on the main system inclusive of parts and labour. Service training for one of the instrumentation staff of CCMB should be provided at the manufacturing facilities abroad. This should be an extensive training programme covering the repair, maintenance and calibration aspects of the system and should form a part of the official service training course at the manufacturing facilities abroad. The above training to be offered free of cost including tution fees, To and fro airfare from Hyderabad to the place of training, boarding, lodging and all living expenses. Availability of local service and application support and response time for a service call during and after warranty to be specified. Spares for the system should be available for a minimum period of 8 years and confirmation to be given in the offer. The year in which the offered model was introduced into the market and the number of installations in India and all over the world over the last three years should be mentioned. List of users worldwide and in India along with the names, email ID’s and telephone numbers of the customers to be enclosed in the offer in separate annexures. All other clauses of warranty, delivery schedule, payment details to be clearly mentioned Apart from meeting the specifications, features and clauses, selection of the system would also be based on the response to all the points mentioned above and hence please respond to all the points. BID DOCUMENT (YC) Page 63 of 63
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CENTRE FOR CELLULAR & MOLECULAR BIO
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VERY IMPORTANT: Pre-Bid Conference
Page 5 and 6:
CHAPTER - II: INSTRUCTION TO BIDDER
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10 Documents Establishing Bidder’
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E. OPENING AND EVALUATION OF BIDS T
Page 11 and 12: CHAPTER - III: GENERAL CONDITIONS O
Page 13 and 14: 15.2This warranty shall remain vali
Page 15 and 16: CHAPTER - IV: SPECIAL CONDITIONS OF
Page 17 and 18: 17 Supplier Integrity 17.1The Suppl
Page 19 and 20: CHAPTER - VI: BID SECURITY FORM Whe
Page 21 and 22: CHAPTER - VIII: BIDDER’S PERFORMA
Page 23 and 24: CHAPTER - X: DEVIATION STATEMENT FO
Page 25 and 26: CHAPTER - XII: CONTRACT FORM THIS A
Page 27 and 28: CHAPTER XIV: QUALIFICATION REQUIREM
Page 29 and 30: ITEM NO.2 - FLUORESCENCE MICROSCOPE
Page 31 and 32: 3. Ambient temperature: 42 deg. C 4
Page 33 and 34: ITEM NO.5 - HIGH RESOLUTION FTIR SY
Page 35 and 36: ITEM NO.6 - PROTEIN PURIFICATION SY
Page 37 and 38: ITEM NO.7 - PHOSPHOR IMAGER ALONG W
Page 39 and 40: ITEM NO.8 - UPRIGHT FLUORESCENCE MI
Page 41 and 42: ITEM NO.9 - ADVANCED MOTORIZED INVE
Page 43 and 44: ITEM NO.10 - SPECTRAL CONFOCAL MICR
Page 45 and 46: ITEM NO.11 - HIGH RESOLUTION MASS S
Page 47 and 48: ITEM NO.12 - HIGH SENSITIVITY CD SP
Page 49 and 50: 2. All the above mentioned technica
Page 51 and 52: . The computer and printer offered
Page 53 and 54: 2. Cost should include three years
Page 55 and 56: 2. Capacity : 8 x 5 ml or more Maxi
Page 57 and 58: ITEM NO.17 - ZEBRA FISH IMAGING AND
Page 59 and 60: ITEM NO.18 - HIGH CONTENT SCREENING
Page 61: 7. Software supplied should be the
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