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The Effect of Medical Advances on Insurance ... - Actuary.com

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Mutati<strong>on</strong>s: Basis for Disease<br />

• A change in DNA Code sequence in a gene<br />

al<strong>on</strong>g a chromosome<br />

• Can be silent, beneficial, deleterious<br />

• <str<strong>on</strong>g>Effect</str<strong>on</strong>g> depends <strong>on</strong> scale <str<strong>on</strong>g>of</str<strong>on</strong>g> change and<br />

area affected<br />

- Large scale versus small scale<br />

- Coding versus n<strong>on</strong> coding regi<strong>on</strong>

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