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The Effect of Medical Advances on Insurance ... - Actuary.com

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Genetic Testing Regulatory<br />

Challenge: Percepti<strong>on</strong> vs. Reality<br />

• Except in rare single gene disorders, a genetic<br />

mutati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g>ten does not = disease<br />

• Most <strong>com</strong>m<strong>on</strong> disorders are multi-factorial and<br />

<str<strong>on</strong>g>of</str<strong>on</strong>g>ten can be favorably influenced by early<br />

diagnosis, treatment and/or behavioral changes<br />

(CAD, DM, BRCA-1/2)<br />

• All <str<strong>on</strong>g>of</str<strong>on</strong>g> us likely have <strong>on</strong>e or more such mutati<strong>on</strong>s<br />

• Genetic testing not cost effective for insurers for<br />

single gene or <strong>com</strong>m<strong>on</strong> <strong>com</strong>plex disorders

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